Search Thermo Fisher Scientific
图: 1 / 7
Positive Samples: SW620, MCF7, Jurkat, BxPC-3, Mouse kidney, Mouse skeletal muscle, Mouse heart, Mouse brain; Cellular Location: Mitochondrion, Mitochondrion inner membrane, Mitochondrion matrix
Immunogen sequence: GLFMREGIVT ATEQEVKEDI AKLLRYESSA LPSGQLTSLS EYASRMRAGT RNIYYLCAPN RHLAEHSPYY EAMKKKDTEV LFCFEQFDEL TLLHLREFDK KKLISVETDI VVDHYKEEKF EDRSPAAECL SEKETEELMA WMRNVLGSRV TNVKVTLRLD THPAMVTVLE MGAARHFLRM QQLAKTQEER AQLLQPTLEI NPRHALIKKL NQLRASEPGL AQLLVDQIYE NAMIAAGLVD DPRAMVGRLN ELLVKALERH
The 90 kDa heat shock protein (hsp90) family of molecular chaperones is a highly conserved family of proteins that play an important physiological role. Hsp90 is involved in numerous cellular processes but is best known for its association with signal transduction machinery. A recently cloned homolog of hsp90 is the tumor necrosis factor receptor-associated protein (TRAP1). Like hsp90, TRAP1 is found to be associated with numerous proteins involved in diverse actions. Immunofluorescence data has shown TRAP1 to be localized in the mitochondria of mammalian cells. This observation and the fact that TRAP1 is shown to have a mitochondrial targeting presequence strongly implicates TRAP1 as a mitochondrial matrix protein.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Heat shock protein 75 kDa, mitochondrial; HSP 75; testicular tissue protein Li 209; TNF receptor-associated protein 1; TNFR-associated protein 1; TRAP-1; tumor necrosis factor type 1 receptor associated protein; Tumor necrosis factor type 1 receptor-associated protein
基因别名: 2410002K23Rik; HSP 75; HSP75; HSP90L; TRAP-1; TRAP1
UniProt ID: (Human) Q12931, (Rat) Q5XHZ0, (Mouse) Q9CQN1
Entrez Gene ID: (Human) 10131, (Rat) 287069, (Mouse) 68015
分子生物学功能: Hsp90 family chaperone