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TRIM5 alpha Antibody (PA5-20051) in IHC
Immunohistochemistry of TRIM5 alpha in human uterus tissue with TRIM5 alpha Polyclonal Antibody (Product # PA5-20051) at 2 µg/mL.
产品信息
PA5-20051
产品规格
种属反应
Human,
Rhesus monkey
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to amino acids near the mid-region of rhesus monkey TRIM5 alpha.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11155842
产品详细信息
In Western blot applications, this antibody detects a band at ~55kDa. A suggested positive control is human stomach tissue lysate.
PA5-20051 can be used with blocking peptide PEP-0170.
靶标信息
The protein encoded by this gene is a member of the tripartite motif family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coiled-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiquitinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HGNC:16276; OTTHUMP00000069812; RING finger protein 88; RING-type E3 ubiquitin transferase TRIM5; TRIM5 alpha; predicted E3 ubiquiting ligase; TRIM5 gamma; predicted E3 ubiquiting ligase; trim5a; TRIM5alpha; tripartite motif containing 5 transcript variant iota; tripartite motif containing 5 transcript variant kappa; tripartite motif protein TRIM5; tripartite motif-containing 5 alpha isoform; tripartite motif-containing 5/cyclophilin A fusion protein; Tripartite motif-containing protein 5; tripartite motif-containing protein 5 isoform alpha
基因别名: RNF88; TRIM5; TRIM5alpha
UniProt ID: (Human) Q9C035, (Rhesus monkey) Q6QWE9
Entrez Gene ID: (Human) 85363, (Rhesus monkey) 574288
