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产品信息
PA5-30309
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein fragment corresponding to a region within amino acids 217 and 429 of Human TRIP15
偶联物
形式
Liquid
浓度
0.99 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2547783
产品详细信息
Recommended positive controls: Raji.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (98%), Xenopus laevis (99%), Pig (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alien homolog; COP9; COP9 constitutive photomorphogenic homolog subunit 2; COP9 signalosome complex subunit 2; JAB1-containing signalosome subunit 2; SGN2; signalosome subunit 2; thyroid receptor interacting protein 15; Thyroid receptor-interacting protein 15; TR-interacting protein 15; TRIP-15
基因别名: ALIEN; COPS2; CSN2; SGN2; TRIP15
UniProt ID: (Human) P61201
Entrez Gene ID: (Human) 9318
negative regulation of transcription from RNA polymerase II promoter
nucleotide-excision repair, DNA damage recognition
transcription-coupled nucleotide-excision repair
transcription from RNA polymerase II promoter
signal transduction
cell proliferation
cullin deneddylation
neuron differentiation
skeletal muscle cell differentiation
negative regulation of nucleic acid-templated transcription
