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Pex5l is an accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence. Research studies have shown that Pex5l is expressed in the brain, testis and pancreas. Diseases associated with PEX5L include Rhizomelic Chondrodysplasia Punctata, Type 5 and Rhizomelic Chondrodysplasia Punctata, Type 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HCN channel auxiliary subunit; peroxin 2; Peroxin-5-related protein; peroxisomal biogenesis factor 5-like; peroxisomal targeting signal 1 receptor-like; Peroxisome biogenesis factor 5-like; PEX2-related protein; PEX5-like protein; PEX5-related protein; Pex5p-related protein; Pex5Rp; Tetratricopeptide repeat-containing Rab8b-interacting protein; TPR-containing Rab8b-interacting protein
基因别名: 1700016J08Rik; Pex2; PEX5L; PEX5R; PEX5RP; PXR2; PXR2B; TRIP8b; Trjip8b
UniProt ID: (Human) Q8IYB4, (Rat) Q925N3, (Mouse) Q8C437
Entrez Gene ID: (Human) 51555, (Rat) 286937, (Mouse) 58869