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TRPM7 Antibody (A302-700A) in WB
Detection of human TRPM7 by western blot. Samples: Whole cell lysate (35 µg) from K-562, LNCaP, Hep-G2, RKO, and HeLa cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-TRPM7 antibody (Product # A302-700A lot 4) used for WB at 1 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.
产品信息
A302-700A
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 1815 and 1865 of Human transient receptor potential cation channel, subfamily M, member 7.
偶联物
形式
Liquid
浓度
0.20 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
靶标信息
TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Channel kinase 1; Channel-kinase 1; FLJ20117; Long transient receptor potential channel 7; LTRPC ion channel family member 7; LTrpC-7; tr; Transient receptor potential cation channel subfamily M member 7; transient receptor potential cation channel, subfamily M, member 7; transient receptor potential M7; Transient receptor potential-phospholipase C-interacting kinase; transient receptor potential-related protein, ChaK; TRMP7; TRP PLIK; TRP-PLIK
基因别名: 2310022G15Rik; 4833414K03Rik; 5033407O22Rik; ALSPDC; CHAK; CHAK1; Ltpr7; LTrpC-7; LTRPC7; TRP-PLIK; TRPM7; TRPPLIK
UniProt ID: (Human) Q96QT4, (Mouse) Q923J1
Entrez Gene ID: (Human) 54822, (Mouse) 58800
actin binding
protein serine/threonine kinase activity
calcium channel activity
ATP binding
myosin binding
metal ion binding
nucleotide binding
protein kinase activity
ion channel activity
cation channel activity
protein binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
ion channel
transporter
cellular magnesium ion homeostasis
calcium-dependent cell-matrix adhesion
actomyosin structure organization
protein autophosphorylation
protein tetramerization
necroptotic process
calcium ion transmembrane transport
protein phosphorylation
transport
ion transport
cation transport
calcium ion transport
memory
programmed cell death
phosphorylation
positive regulation of apoptotic process
transmembrane transport
