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TRPML3 Antibody (PA5-109339) in IHC (P)
Immunohistochemistry analysis of TRPML3 in paraffin-embedded human liver carcinoma tissue. Samples were heat mediated antigen retrieval with sodium citrate buffer (pH 6.0, 20 min) and blocked in 5% BSA (30 min, room temperature), incubated with TRPML3 polyclonal antibody (Product # PA5-109339) at a dilution of 1:50 (30 min, room temperature), and followed by HRP conjugated compact polymer system, DAB, count... View More
产品信息
PA5-109339
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide within Human TRPML3 aa 504-553
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles, store in dark
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2854750
产品详细信息
Positive Control: 293 cell, F9.
靶标信息
Expressed in the cochlea; particularly in the inner and outer hair cells. Defects in Mcoln3 are the cause of the varitin-waddler (Va) phenotype. Classical Va mice exhibit early-onset hearing loss, vestibular defects, pigmentation abnormalities and perinatal lethality. The phenotype varitin-waddler Jackcon (Va-J), which arose in a cross segregating for Va, is similar but less severe. Belongs to the transient receptor family, polycystin subfamily.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ11006; FLJ36629; MCLN3; Mcoln3 mucolipin 3; MGC124245; MGC124246; MGC71509; Mucolipin-3; Transient receptor potential channel mucolipin 3; TRPML3; varitint-waddler
基因别名: 6720490O21Rik; MCOLN3; TRP-ML3; TRPML3; Va
UniProt ID: (Human) Q8TDD5, (Mouse) Q8R4F0
Entrez Gene ID: (Human) 55283, (Mouse) 171166
