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产品信息
H00007251-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TSG101 (ENSP00000251968, 1 a.a. approximately 390 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.24 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAVSESQLKK MVSKYKYRDL TVRETVNVIT LYKDLKPVLD SYVFNDGSSR ELMNLTGTIP VPYRGNTYNI PICLWLLDTY PYNPPICFVK PTSSMTIKTG KHVDANGKIY LPYLHEWKHP QSDLLGLIQV MIVVFGDEPP VFSRPISASY PPYQATGPPN TSYMPGMPGG ISPYPSGYPP NPSGYPGCPY PPGGPYPATT SSQYPSQPPV TTVGPSRDGT ISEDTIRASL ISAVSDKLRW RMKEEMDRAQ AELNALKRTE EDLKKGHQKL EEMVTRLDQE VAEVDKNIEL LKKKDEELSS ALEKMENQSE NNDIDEVIIP TAPLYKQILN LYAEENAIED TIFYLGEALR RGVIDLDVFL KHVRLLSRKQ FQLRALMQKA RKTAGLSDLY
靶标信息
TSG101-4A10 recognizes TSG101 protein, the product of a recently identified Tumor Susceptibility Gene whose inactivation in mouse fibroblasts results in cell transformation and the ability of those cells to form tumors in nude mice. The TSG101 gene encodes a 46 kDa protein and contains a proline-rich domain and a leucine-zipper motif within a coiled-coil domain near the carboxyl terminus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ESCRT-I complex subunit TSG101; ESCRTI complex subunit TSG101; TSG 101; tumor susceptibility gene 10; tumor susceptibility gene 101; Tumor susceptibility gene 101 protein; tumor susceptibility protein
基因别名: TSG10; TSG101; VPS23
UniProt ID: (Human) Q99816
Entrez Gene ID: (Human) 7251
regulation of cell growth
protein monoubiquitination
autophagy
cell cycle arrest
negative regulation of cell proliferation
endosome to lysosome transport
protein transport
endosomal transport
viral life cycle
keratinocyte differentiation
multivesicular body assembly
viral budding via host ESCRT complex
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
regulation of MAP kinase activity
negative regulation of transcription, DNA-templated
viral budding
positive regulation of viral process
cell division
intracellular transport of virus
autophagosome maturation
regulation of viral release from host cell
positive regulation of viral release from host cell
positive regulation of exosomal secretion
regulation of extracellular exosome assembly
regulation of viral budding via host ESCRT complex
positive regulation of viral budding via host ESCRT complex
positive regulation of ubiquitin-dependent endocytosis
