Invitrogen

TSHZ3 Polyclonal Antibody

TSHZ3 Antibody in Immunohistochemistry (IHC)

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TSHZ3 Antibody (PA5-34344) in IHC

Immunohistochemistry of TSHZ3 in mouse brain tissue with TSHZ3 Polyclonal Antibody (Product # PA5-34344) at 2.5 µg/mL.

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产品信息

PA5-34344

应用

建议稀释比

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免疫印迹 (WB)

1 µg/mL

免疫组化 (IHC)

2.5 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

An 18 amino acid synthetic peptide near the amino terminus of human TSHZ3

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

0.02% sodium azide

保存条件

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2551696

产品详细信息

A suggested positive control is mouse brain tissue lysate.

PA5-34344 can be used with blocking peptide PEP-1387.

靶标信息

The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. In mice, the known three TSHZ proteins are expressed in distinct patterns in the developing and adult brain, suggesting that they play a role in the establishment of regional identity and specification of cell types within the brain. Both TSHZ3 and TSHZ1 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4. Recent experiments have also suggested this family of proteins may be involved in carcinogenesis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。