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This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: ATDSRTPEVP AGEGPRRGLG APLTEDQQNR LSEEIEKKWQ ELEKLPLREN KRVPLTALLN QSRGERRGPP SDGHEALEKE VQALRAQLEA WRLQGEAPQS A
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 85%.
This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Protein Tara; tara-like protein; TRF1-associated protein of 68 kDa; TRIO and F-actin-binding protein; Trio-associated repeat on actin
基因别名: AI428493; DFNB28; dJ37E16.4; EST478828; HRIHFB2122; KIAA1662; mKIAA1662; TAP68; TARA; TRIOBP
UniProt ID: (Human) Q9H2D6, (Mouse) Q99KW3
Entrez Gene ID: (Human) 11078, (Rat) 362956, (Mouse) 110253