Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Application
图: 1 / 1
Tenascin R Antibody (PA5-47546) in IHC (P)
Immunohistochemical analysis of Tenascin R in immersion fixed paraffin-embedded sections of human brainstem (medulla). Samples were incubated in Tenascin R polyclonal antibody (Product # PA5-47546) using a dilution of 1.7 µg/mL overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue).
产品信息
PA5-47546
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant human Tenascin R isoform 1 Glu34-Phe1358
偶联物
Unconjugated
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2606261
产品详细信息
In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human Tenascin C is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
Tenascin-R (TNR) is an extracellular matix protein expressed primarily in the central nervous system. It is a member of the tenascin (TN) gene family, which includes at least 3 genes in mammals: TNC (or hexabrachion; MIM 187380), TNX (TNXB; MIM 600985), and TNR (Erickson, 1993). The genes are expressed in distinct tissues at different times during embryonic development and are present in adult tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Janusin; Restrictin; Tenascin-R; TN-R
基因别名: TN-R; TNR
UniProt ID: (Human) Q92752
Entrez Gene ID: (Human) 7143
cell adhesion
neuron cell-cell adhesion
axon guidance
associative learning
telencephalon cell migration
negative regulation of cell-cell adhesion
extracellular matrix organization
locomotory exploration behavior
negative regulation of axon extension involved in regeneration
negative regulation of synaptic transmission
synapse organization
neuromuscular process controlling balance
positive regulation of synaptic transmission, glutamatergic
positive regulation of transmission of nerve impulse
long-term synaptic potentiation
