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Tet Antibody (PA5-144574) in WB
Western blot analysis of Tet in recombinant protein using a dilution of 1:1,000. Samples were incubated with Tet polyclonal antibody (Product # PA5-144574). Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 47 kDa. Observed band size: 47 kDa.
产品信息
PA5-144574
产品规格
种属反应
Fruit fly
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Fruit fly Tet protein (2494-2767aa)
偶联物
形式
Liquid
浓度
2.808 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% Proclin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_3091668
靶标信息
Dioxygenase that specifically demethylates DNA methylated on the 6th position of adenine (N(6)-methyladenosine) DNA (PubMed:25936838, PubMed:30078725). N(6)-methyladenosine (m6A) DNA is present at a relatively high level at the very earliest embryonic stages but at low levels at the late embryonic stages and may act as a regulator of gene expression (PubMed:25936838). Promotes differentiation of early germ cells in ovary (PubMed:25936838). Contributes to neuronal morphology, development, and function in the brain (PubMed:30078725). By interacting with histone modifier wds, binds to a specific set of genes, modulates intragenic (N(6)-methyladenosine) DNA levels and thereby maintains transcriptional activation (PubMed:30078725). Also able to catalyze the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) (PubMed:25936838).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CG43444-PA; CG43444-PB; CG43444-PC; CG43444-PD; CG43444-PE; CG43444-PF; DMAD; DNA 6mA demethylase; DNA N6-methyl adenine demethylase; Methylcytosine dioxygenase TET; TET family protein; Tet-PA; Tet-PB; Tet-PC; Tet-PD; Tet-PE; Tet-PF
基因别名: CG2083; CG43444; CG9973; DMAD; Dmel\CG43444; Dmel_CG43444; DNA 6mA; dTET; Idax; Tet
UniProt ID: (Fruit fly) M9NEY8
Entrez Gene ID: (Fruit fly) 38347
