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Immunogen sequence: WTSTHGGSGS RQGRQDGDQD APDIRNRFPN FLGIIRLYDY LQQLHENPQS LGTYLQGTAS ALSQSQEPPP SVNRVPPSSP SSQEPGSGQP LPEESVAIKG RSSCPAFLRY PTENSTGQGG DQDGAGKSST GHSTNLPDLV SGLGDSANRV PFAPLSFSPT AAIPGIPEPP WLPSPAYPRS LRPDGMNPAP QLQDEIQPQL PLLMHLQAAM ANPRALQALR QIEQGLQVLA TEAPRLLLWF MPCLAGTGSV AGGIESREDP LMSEDPLPNP PPEVFPALDS AELGFLSPPF LHMLQDLVST NPQQLQPEAH FQVQL
This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This gene is specifically expressed in the testis, and proposed to regulate cell-cycle progression during spermatogenesis.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: testicular tissue protein Li 220; Ubiquilin-3
基因别名: 4933400K24Rik; TUP-1; UBQLN3
UniProt ID: (Human) Q9H347, (Mouse) Q8C5U9
Entrez Gene ID: (Human) 50613, (Mouse) 244178, (Rat) 308905