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Positive test controls include: Raji, A-549, HT-29, RAW264.7, Mouse heart, Rat heart. The target is usually found in the following locations: Mitochondrion inner membrane, Multi-pass membrane protein.
Immunogen sequence: EHASIGSRLL AGSTTGALAV AVAQPTDVVK VRFQAQARAG GGRRYQSTVN AYKTIAREEG FRGLWKGTSP NVARNAIVNC AELVTYDLIK DALLKANLMT
UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. UCP2 gene is expressed in many tissues, with the greatest expression in skeletal muscle. UCP2 is thought to play a role in non shivering thermogenesis, obesity and diabetes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Dicarboxylate carrier SLC25A8; Mitochondrial uncoupling protein 2; Solute carrier family 25 member 8; UCP 2; UCPH; uncoupling protein; uncoupling protein 2 (mitochondrial, proton carrier); Uncoupling protein 2, mitochondrial
基因别名: BMIQ4; SLC25A8; UCP2; UCPH
UniProt ID: (Human) P55851, (Rat) P56500, (Mouse) P70406
Entrez Gene ID: (Human) 7351, (Rat) 54315, (Mouse) 22228
分子生物学功能:
transporter
secondary carrier transporter