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The protein encoded by this gene belongs to the UDP-glycosyltransferase family, members of which catalyze biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This enzyme is expressed in the olfactory neuroepithelium, which lines the posterior nasal cavity and is exposed to a wide range of odorants and airborne toxic compounds. Hence, this protein has been suggested to be involved in clearing lipophilic odorant molecules from the sensory epithelium. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. This gene shares exon structure with the UDP glucuronosyltransferase 2A2 family member, which encodes N-terminally distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus; UDP glycosyltransferase 2 family, polypeptide A1; UDP-glucuronosyltransferase 2A1; UDPGT 2A1; uridine diphosphate glycosyltransferase 2 family, member A1
基因别名: UDPGT2A1; UGT2A1
UniProt ID: (Human) P0DTE4
Entrez Gene ID: (Human) 10941