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Immunogen sequence: TGYKYEGVKF EKGNCGVSIM RSGEAMEQGL RDCCRSIRIG KILIQSDEET QRAKVYYAKF PPDIYRRKVL LMYPILSTGN TVIEAVKVLI EHGVQPSVII LLSLFSTPHG AKSIIQEFPE IT^M
^M
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: RP11-311P8.3; UMP pyrophosphorylase; UPRTase; uracil phosphoribosyltransferase (FUR1) homolog; Uracil phosphoribosyltransferase homolog
基因别名: FUR1; UPP; UPRT
UniProt ID: (Human) Q96BW1
Entrez Gene ID: (Human) 139596