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Uteroglobin Antibody (MA5-50171) in Flow
Flow cytometry analysis overlay peak curve showing A549 cells stained with Uteroglobin monoclonal antibody (Product # MA5-50171) for 45 min at 4. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at (1x10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed.
产品信息
MA5-50171
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
21B2
抗原
A synthesized peptide derived from Human SCGB1A1
偶联物
形式
Liquid
浓度
0.33 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_3092586
靶标信息
Uteroglobin, which is a member of the Secretoglobin superfamily and is also known as Clara cell phospholipid-binding protein, is a multifunctional protein that can exert anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. The small, non-glycosylated protein named for its high levels of expression in pre-implantation embryos, where it exhibits growth stimulatory effects, is produced and secreted by the non-ciliated, non-mucous Clara cells predominant in the epithelial surfaces of pulmonary airways, as well as other non-ciliated epithelia. Members of the Secretoglobin superfamily demonstrate a high level of structural conservation and are characterized as small, secretory homo- or heterodimers. In addition to sequestering pro-inflammatory mediators and carcinogens, Uteroglobin has been implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: blastokinin; CC10; CCPBP; clara cell phospholipid-binding protein; clara cells 10 kDa secretory protein; Club cell phospholipid-binding protein; Club cells 10 kDa secretory protein; Secretoglobin family 1A member 1; secretoglobin, family 1A, member 1 (uteroglobin); UP-1; Urinary protein 1; urine protein 1; Uteroglobin
基因别名: CC10; CC16; CCPBP; CCSP; SCGB1A1; UGB; UP-1; UP1
UniProt ID: (Human) P11684
Entrez Gene ID: (Human) 7356
negative regulation of transcription from RNA polymerase II promoter
signal transduction
female pregnancy
embryo implantation
response to xenobiotic stimulus
response to ozone
response to lipopolysaccharide
negative regulation of interferon-gamma production
negative regulation of interleukin-13 production
negative regulation of interleukin-4 production
negative regulation of interleukin-5 production
response to silicon dioxide
response to cytokine
negative regulation of T cell proliferation
response to drug
negative regulation of catalytic activity
regulation of mRNA stability
regulation of inflammatory response
response to glucocorticoid
response to fibroblast growth factor
