Invitrogen

VASH1 Polyclonal Antibody

VASH1 Antibody in Immunohistochemistry (IHC)

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VASH1 Antibody (PA5-21148) in IHC

Immunohistochemistry of VASH1 in mouse brain tissue with VASH1 Polyclonal Antibody (Product # PA5-21148) at 5 µg/mL.

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产品信息

PA5-21148

应用

建议稀释比

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免疫印迹 (WB)

1 µg/mL

免疫组化 (IHC)

5 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A 19 amino acid peptide near the carboxy terminus of human VASH1.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

0.02% sodium azide

保存条件

4° C

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_11152639

产品详细信息

A suggested positive control is human brain tissue lysate.

PA5-21148 can be used with blocking peptide PEP-1262.

靶标信息

VASH1 is a protein that possesses actin binding activity and metallocarboxypeptidase activity. It is involved in several processes including negative regulation of angiogenesis, negative regulation of blood vessel endothelial cell migration, and proteolysis. VASH1 acts upstream of or within processes such as negative regulation of endothelial cell migration, negative regulation of endothelial cell proliferation, and negative regulation of lymphangiogenesis. It is located in the apical part of the cell, endoplasmic reticulum, and extracellular space. VASH1 is implicated in liver cirrhosis and portal hypertension, and is a biomarker of liver cirrhosis. Diseases associated with VASH1 include Portal Hypertension and Myasthenic Syndrome, Congenital, 14.

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