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VDAC2 Antibody (PA5-116112) in ICC/IF
Immunocytochemistry analysis of VDAC2 in HepG2. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-116112) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
产品信息
PA5-116112
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human VDAC2(Accession P45880), corresponding to amino acid residues R263-A294.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2900746
产品详细信息
Antibody detects endogenous levels of total VDAC2.
靶标信息
This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B36-VDAC; FLJ23841; Outer mitochondrial membrane protein porin 2; RP11-375G3.1; VDAC-2; VDAC-6; voltage-dependent anion channel 2; Voltage-dependent anion-selective channel protein 2; Voltage-dependent anion-selective channel protein 6
基因别名: mVDAC2; mVDAC6; POR; VDAC2; Vdac6
UniProt ID: (Human) P45880, (Mouse) Q60930, (Rat) P81155
Entrez Gene ID: (Human) 7417, (Mouse) 22334, (Rat) 83531
