Invitrogen

VGF Polyclonal Antibody

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VGF Antibody (PA5-42113) in WB

Western blot analysis of transfected 293T cells using an anti-VGF polyclonal antibody (Product # PA5-42113).

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产品信息

PA5-42113

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.2-1 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide directed towards the middle region of human VGF

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2610369

产品详细信息

Peptide sequence: ARQNALLFAE EEDGEAGAED KRSQEETPGH RRKEAEGTEE GGEEEDDEEM

Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%

靶标信息

VGF was initially identified as a rapidly regulated gene product in nerve growth factor-treated PC12 cells. This protein is synthesized in neurons in the central and peripheral nervous system as well as in the pituitary, adrenal medulla, endocrine cells of the stomach, and pancreatic beta cells. VGF is thought to be involved in organism energy balance and regulation of homeostasis as mice lacking this gene show deficits in these areas. More recent results suggest that VGF is upregulated by brain-derived neurotrophic factor (BDNF) and can stimulate the proliferation of hippocampal progenitor cells and produce antidepressant-like behavioral effects, suggesting that this pathway may be a suitable target for therapeutic treatments.

仅用于科研。不用于诊断过程。未经明确授权不得转售。