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VMAT2 Antibody (AMT-006-200UL) in IHC (F)
Expression of VMAT2 in rat substantia nigra dopaminergic neurons - Immunohistochemical staining of perfusion-fixed frozen rat brain sections using Anti-VMAT2 Antibody (#AMT-006), (1:1000). A. VMAT2 staining (red). B. Tyrosine hydroxylase staining (green), a marker of dopaminergic neurons. C. Merger of A and B demonstrates VMAT2 expression in several dopaminergic neurons (arrows). Cell nuclei were stained wi... View More
产品信息
AMT-006-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)KHEKNSTEIQT(A)R, corresponding to amino acid residues 52-64 of rat VMAT2, 1stluminal loop
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
VMAT2 is involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. It is a requisite for vesicular amine storage prior to secretion via exocytosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC120477; MGC120478; MGC26538; monoamine neurotransmitter transporter; Monoamine transporter; solute carrier family 18 (vesicular monoamine transporter), member 2; solute carrier family 18 (vesicular monoamine), member 2; Solute carrier family 18 A2 (vesicular monoamine transporter 2); Solute carrier family 18 member 2; solute carrier family 18, member 2; Synaptic vesicular amine transporter; VAT2; vesicle monoamine transporter type 2; vesicle monoamine/H+ antiporter; Vesicular amine transporter 2; vesicular monoamine transporter 2
基因别名: 1110037L13Rik; 9330105E13; MNAT; SLC18A2; SVAT; SVMT; VAT2; VMAT-2; VMAT2
UniProt ID: (Human) Q05940, (Mouse) Q8BRU6, (Rat) Q01827
Entrez Gene ID: (Human) 6571, (Mouse) 214084, (Rat) 25549
response to amphetamine
serotonin transport
chemical synaptic transmission
neurotransmitter secretion
aging
locomotory behavior
response to herbicide
post-embryonic development
response to zinc ion
aminergic neurotransmitter loading into synaptic vesicle
monoamine transport
dopamine transport
insulin secretion
endocytic recycling
cellular response to drug
sequestering of neurotransmitter
response to cocaine
glucose homeostasis
response to starvation
response to corticosterone
negative regulation of neurotransmitter transport
transmembrane transport
cellular response to ammonium ion
neurotransmitter loading into synaptic vesicle
negative regulation of reactive oxygen species biosynthetic process
transport
neurotransmitter transport
response to toxic substance
organic cation transport
drug transport
obsolete death
ammonium transmembrane transport
drug transmembrane transport
response to metal ion
response to drug
