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This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human VNN2/Vanin-2.
This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Glycosylphosphatidyl inositol-anchored protein GPI-80; pantetheinase; Pantetheine hydrolase VNN2; Protein FOAP-4; Vanin-2; Vannin 2; Vascular non-inflammatory molecule 2
基因别名: FOAP-4; GPI-80; VNN2
UniProt ID: (Human) O95498
Entrez Gene ID: (Human) 8875