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This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Hepatocellular carcinoma protein 8; protein phosphatase 1, regulatory subunit 164; Tumor antigen HOM-HCC-8; Tumor antigen SLP-8p; Tumor antigen SLP-8p homolog; vacuolar protein sorting 54 homolog; Vacuolar protein sorting-associated protein 54; VPS54 GARP complex subunit
基因别名: HCC8; hVps54L; mSLP8; PPP1R164; SLP-8p; VPS54; VPS54L; WR
UniProt ID: (Human) Q9P1Q0, (Mouse) Q5SPW0
Entrez Gene ID: (Human) 51542, (Mouse) 245944
分子生物学功能: membrane traffic protein