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Immunogen sequence: ASREQLSIQW SFFHKKEMEP ISIYFSQGGQ AVAIGQFKDR ITGSNDPGNA SITISHMQPA DSGIYICDVN NPPDFLGQNQ GILNVSVLVK PSKPLCSVQG RPETGHTISL SCLSALGTPS PVYYWHKLEG RDIVPVKENF NPTTGILVIG NLTNFEQGYY QCTAINRLGN SSCEIDLTSS H; Positive Samples: BxPC3, OVCAR3, Mouse testis, Mouse stomach, Mouse pancreas; Cellular Location: Membrane, Single-pass type I membrane protein
VSIG1 encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in normal stomach and testis, as well as in gastric, esophageal and ovarian cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cell surface A33 antigen; Glycoprotein A34; MGC44287; V-set and immunoglobulin domain-containing protein 1
基因别名: 1700062D20Rik; 4930405J24Rik; dJ889N15.1; GPA34; VSIG1
UniProt ID: (Human) Q86XK7, (Mouse) Q9D2J4, (Rat) Q4KLY3
Entrez Gene ID: (Human) 340547, (Mouse) 78789, (Rat) 315920
分子生物学功能: defense/immunity protein immunoglobulin receptor superfamily