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This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein is highly similar to the mouse WD repeat domain 12 protein at the amino acid level. The protein encoded by this gene is a component of a nucleolar protein complex that affects maturation of the large ribosomal subunit.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ribosome biogenesis protein WDR12; WD repeat-containing protein 12; WDR12
基因别名: WDR12; YTM1
UniProt ID: (Human) Q9GZL7
Entrez Gene ID: (Human) 55759