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WDR77 Antibody (MA5-50769) in IHC (P)
Immunohistochemistry of WDR77 in paraffin-embedded human fallopian tube tissue. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 2 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with WDR77 recombinant monoclonal antibody (Product # MA5-50769) with a dilution of 1:1,000 for 1 h... View More
产品信息
MA5-50769
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
PSH0-07
抗原
Recombinant protein within human WDR77 aa 1-342/342.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3092882
产品详细信息
Positive control: Human prostate tissue, human fallopian tube tissue, mouse brain tissue, HepG2 cell lysate, 293 cell lysate, K562 cell lysate, Hela, HepG2.
Predicted band size: 37 kDa
Subcellular Location: Nucleus, Cytoplasm.
靶标信息
WDR77 is a component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Androgen receptor cofactor p44; MEP-50; Methylosome protein 50; Methylosome protein WDR77; MGC2722; OTTHUMP00000013473; p44/Mep50; RP11-552M11.3; testis tissue sperm-binding protein Li 44a; WD repeat-containing protein 77
基因别名: HKMT1069; MEP-50; MEP50; Nbla10071; p44; p44/Mep50; WD45; WDR77
UniProt ID: (Human) Q9BQA1
Entrez Gene ID: (Human) 79084
spliceosomal snRNP assembly
regulation of transcription from RNA polymerase II promoter
positive regulation of cell proliferation
peptidyl-arginine N-methylation
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
negative regulation of epithelial cell proliferation involved in prostate gland development
