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产品信息
PA5-76762
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human WNK3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2720489
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
WNK3 is a serine/threonine kinase involved in signal transduction and cellular communication. Members of the 'with no lysine' kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PRKWNK 3; Protein kinase lysine-deficient 3; Protein kinase with no lysine 3; Serine/threonine-protein kinase WNK3; WNK 3; WNK lysine deficient protein kinase 3, pseudogene
基因别名: KIAA1566; PRKWNK3; RGD1563131; WNK3; Wnk3-ps
UniProt ID: (Human) Q9BYP7, (Mouse) Q80XP9
Entrez Gene ID: (Human) 65267, (Mouse) 279561, (Rat) 317420
protein phosphorylation
positive regulation of sodium ion transport
positive regulation of peptidyl-threonine phosphorylation
positive regulation of ion transmembrane transporter activity
intracellular signal transduction
negative regulation of apoptotic process
protein autophosphorylation
positive regulation of calcium ion transport
positive regulation of establishment of protein localization to plasma membrane
negative regulation of pancreatic juice secretion
regulation of ion homeostasis
positive regulation of sodium ion transmembrane transporter activity
positive regulation of rubidium ion transport
positive regulation of rubidium ion transmembrane transporter activity
phosphorylation
