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产品信息
PA5-116127
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human WNT16(Accession Q9UBV4), corresponding to amino acid residues L285-R335.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2900761
产品详细信息
Antibody detects endogenous levels of total WNT16.
靶标信息
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen. WNT15 is also a ligand for members of the frizzled family of seven transmembrane receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Protein Wnt-16; wingless-related MMTV integration site 16; wingless-type MMTV integration site family member 16; wingless-type MMTV integration site family member 16b; wingless-type MMTV integration site family, member 16
基因别名: WNT16
UniProt ID: (Human) Q9UBV4
Entrez Gene ID: (Human) 51384, (Rat) 500047
optic cup formation involved in camera-type eye development
positive regulation of gene expression
positive regulation of phosphatidylinositol 3-kinase signaling
Wnt signaling pathway
neuron differentiation
keratinocyte differentiation
keratinocyte proliferation
cell fate commitment
positive regulation of JNK cascade
bone remodeling
cardiac epithelial to mesenchymal transition
negative regulation of cell death
replicative senescence
oxidative stress-induced premature senescence
biological_process
