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WNT2B Antibody (710888) in ICC/IF
Immunofluorescence was performed on methanol fixed MDA-MB-231 cells for detection of WNT2B/13 using Anti-WNT2B/13 Recombinant Rabbit Monoclonal Antibody (Product # 701856, 2 µg/mL), alpha-Tubulin Monoclonal Antibody (Product # 32-2500, 1 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000), Goat anti-Mouse IgG Secondary Antibody, Alexa Fluor® 594conjugate (Product # A-11032, 1:400) respectively. Panel a) shows representative cells that were stained... View More
产品信息
710888
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Superclonal
类型
Antibody
克隆号
17HCLC
抗原
Peptides corresponding to Human WNT2B (aa 286-298, 253-267, 380-391)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2606216
产品详细信息
This antibody is predicted to react with Monkey, Pig and Rabbit.
Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.
靶标信息
WNT2B is a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. It may play a role in human development as well as human carcinogenesis. Two alternatively spliced transcript variants exist.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Protein Wnt-13; Protein Wnt-2b; wingless related MMTV integration site 2b; wingless-type MMTV integration site family member 2B; wingless-type MMTV integration site family, member 13; wingless-type MMTV integration site family, member 2B; wnt-13; XWNT2, Xenopus, homolog of
基因别名: WNT13; WNT2B
UniProt ID: (Human) Q93097, (Mouse) O70283
Entrez Gene ID: (Human) 7482, (Mouse) 22414
chondrocyte differentiation
lens development in camera-type eye
male gonad development
cellular response to starvation
Wnt signaling pathway
forebrain regionalization
neuron differentiation
cell fate commitment
canonical Wnt signaling pathway
lung induction
mesenchymal-epithelial cell signaling
iris morphogenesis
cornea development in camera-type eye
hematopoietic stem cell proliferation
positive regulation of branching involved in ureteric bud morphogenesis
positive regulation of canonical Wnt signaling pathway
signal transduction
cell-cell signaling
multicellular organism development
organ morphogenesis
