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WNT7B Antibody (PA5-103480) in ICC/IF
Immunocytochemistry analysis of WNT7B in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with WNT7B polyclonal antibody (Product # PA5-103480) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-103480
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human WNT7B(Accession P56706), corresponding to amino acid residues N276-C326.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2852816
产品详细信息
Antibody detects endogenous levels of total WNT7B.
靶标信息
Wnt7b encodes a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Among members of the human WNT family, this gene product is most similar to WNT7A protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Protein Wnt-7b; wingless-related MMTV integration site 7B; wingless-type MMTV integration site family member 7B; wingless-type MMTV integration site family, member 7B
基因别名: Wnt-7b; WNT7B
UniProt ID: (Human) P56706, (Mouse) P28047
Entrez Gene ID: (Human) 7477, (Rat) 315196, (Mouse) 22422
in utero embryonic development
metanephros morphogenesis
Wnt signaling pathway
establishment or maintenance of polarity of embryonic epithelium
forebrain regionalization
central nervous system vasculogenesis
neuron differentiation
lung development
oxygen homeostasis
homeostatic process
cellular metabolic process
cell fate commitment
positive regulation of osteoblast differentiation
fibroblast proliferation
embryonic organ development
synapse organization
canonical Wnt signaling pathway
lung morphogenesis
lung epithelium development
lobar bronchus development
trachea cartilage morphogenesis
developmental growth involved in morphogenesis
embryonic placenta morphogenesis
chorio-allantoic fusion
mammary gland epithelium development
lens fiber cell development
cellular response to retinoic acid
renal inner medulla development
renal outer medulla development
outer medullary collecting duct development
inner medullary collecting duct development
stem cell proliferation
metanephric collecting duct development
metanephric epithelium development
metanephric loop of Henle development
angiogenesis
vasculature development
activation of JUN kinase activity
positive regulation of cell proliferation
positive regulation of gene expression
cell proliferation in forebrain
neuron projection development
regulation of cell projection size
odontogenesis of dentin-containing tooth
negative regulation of smoothened signaling pathway
positive regulation of JNK cascade
neuron projection morphogenesis
stem cell development
negative regulation of neurogenesis
smooth muscle cell differentiation
response to glucocorticoid
anatomical structure regression
lung-associated mesenchyme development
apoptotic process involved in patterning of blood vessels
signal transduction
multicellular organism development
positive regulation of receptor activity
