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产品信息
MA5-18280
产品规格
种属反应
Virus
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
H79H
抗原
West Nile Virus native protein
偶联物
形式
Liquid
浓度
100 µg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2
内含物
0.1% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2539654
产品详细信息
This antibody is specific for the envelope protein of West Nile Virus. It detects West Nile Virus, St. Louis Encephalitis, Japanese Encephalitis and Dengue, and does not react with Yellow Fever, Tick-Borne Encephalitis, Eastern Equine Encephalitis, Western Equine Encephalitis, Powassan, La Crosse Encephalitis or Venezuelan Equine Encephalitis.
Purity is >90%.
靶标信息
West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins which play a major role for WNV entry into target cells. The viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway as delivery of core gene delivery into the striatum of mouse brain and skeletal muscle resulted in cell death and inflammation.
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生物信息学
蛋白别名: West Nile envelope; West Nile Virus; WNV envelope
