Invitrogen

YEATS2 Polyclonal Antibody

产品信息

PA5-147120

应用

建议稀释比

已发表文章

免疫组化 (IHC)

1:500-1:1,000

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human YEATS2

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.6 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

产品详细信息

Immunogen sequence: GLLKVSEGSK TCDTMVFNHP AIKKFLESPS RSSSPANQRA ETPSANHSES DSLSQHNDFL SDKDNNSNMD IEERLSNNME QRPSRNTGRD T

Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 87%.

靶标信息

The YEATS domain-containing protein 2 (YEATS2) is a nuclear protein that is phosphorylated upon DNA damage by ATM or ATR and contains 1 YEATS domain. The gene encoding YEATS2 resides on chromosome 3, which contains about 214 million bases encoding over 1, 100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B.

仅用于科研。不用于诊断过程。未经明确授权不得转售。