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YOD1 Antibody (PA5-89126) in WB
Western blot analysis of YOD1 in K-562 cells. Samples were incubated with YOD1 Polyclonal antibody (Product # PA5-89126) using a dilution of 1:800, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
产品信息
PA5-89126
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-348 of human YOD1 (NP_0610363)
偶联物
Unconjugated
形式
Liquid
浓度
0.46 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2805371
产品详细信息
Immunogen sequence: MFGPAKGRHF GVHPAPGFPG GVSQQAAGTK AGPAGAWPVG SRTDTMWRLR CKAKDGTHVL QGLSSRTRVR ELQGQIAAIT GIAPGGQRIL VGYPPECLDL SNGDTILEDL PIQSGDMLII EEDQTRPRSS PAFTKRGASS YVRETLPVLT RTVVPADNSC LFTSVYYVVE GGVLNPACAP EMRRLIAQIV ASDPDFYSEA ILGKTNQEYC DWIKRDDTWG GAIEISILSK FYQCEICVVD TQTVRIDRFG EDAGYTKRVL LIYDGIHYDP LQRNFPDPDT PPLTIFSSND DIVLVQALEL ADEARRRRQF TDVNRFTLRC MVCQKGLTGQ AEAREHAKET GHTNFGEV; Positive Samples: Mouse brain
靶标信息
Deubiquitinating enzymes (DUBs) are proteases that specifically cleave ubiquitin linkages, negating the action of ubiquitin ligases. DUBA8 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DUBA-8; HIN-7; HIV-1-induced protease 7; HIV-induced protein-7-like protease; hsHIN7; OTU domain containing 2; OTU domain-containing protein 2; Ubiquitin thioesterase OTU1; YOD1 OTU deubiquinating enzyme 1 homolog ( yeast)
基因别名: 9930028C20Rik; DUBA8; HIN7; Hshin7; OTUD2; PRO0907; YOD1
UniProt ID: (Human) Q5VVQ6, (Mouse) Q8CB27
Entrez Gene ID: (Human) 55432, (Mouse) 226418
thiol-dependent ubiquitin-specific protease activity
protein binding
ubiquitin protein ligase binding
metal ion binding
Lys63-specific deubiquitinase activity
ubiquitin-specific protease activity involved in negative regulation of retrograde protein transport, ER to cytosol
Lys48-specific deubiquitinase activity
peptidase activity
cysteine-type peptidase activity
hydrolase activity
cysteine protease
ER-associated ubiquitin-dependent protein catabolic process
endoplasmic reticulum unfolded protein response
protein K29-linked deubiquitination
protein K11-linked deubiquitination
protein K63-linked deubiquitination
protein K48-linked deubiquitination
negative regulation of retrograde protein transport, ER to cytosol
protein K27-linked deubiquitination
protein K33-linked deubiquitination
proteolysis
response to unfolded protein
