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Immunogen sequence: TASGSNSPTS DSASVQRADT SLNNCEGAAG STSEKSRNVP VAALPVTQQM TEMSISREDK ITTPKTEVSE PVVTQPSPSV SQPSTSQSEE KAPELPKPKK
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%.
ZNF216 (ZFAND5) is a potent inhibitory factor for osteoclast differentiation and the mechanism is unlikely due to direct attenuation of the NF-kappa B pathway. It also has redundant and distinct roles in regulating apoptosis.
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