Invitrogen

ZFP36L1 Polyclonal Antibody

ZFP36L1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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ZFP36L1 Antibody (PA5-68592) in IHC (P)

Immunohistochemical analysis of ZFP36L1 in paraffin-embedded human heart tissue. Sample was probed with a ZFP36L1 polyclonal antibody (Product # PA5-68592) at a dilution of 1:600. Detection was performed with a donkey anti-Rabbit Cy3 secondary antibody at a dilution of 1:200. Images were taken at 20x magnification with an exposure time of 0.5-2.0 seconds.

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产品信息

PA5-68592

应用

建议稀释比

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免疫印迹 (WB)

0.2-1.0 µg/mL

免疫组化 (IHC)

1:600

免疫组化（石蜡） (IHC (P))

Assay-Dependent

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

synthetic peptide directed towards the N terminal region of human BRF1/BRF2

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2688604

产品详细信息

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 92%; Human: 100%; Mouse: 92%; Pig: 100%; Rat: 92%

靶标信息

This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: Butyrate response factor 1; early response factor Berg36; EGF-response factor 1; ERF-1; mRNA decay activator protein ZFP36L1; TPA-induced sequence 11b; ZFP36 ring finger protein-like 1; ZFP36-like 1; zinc finger protein 36, C3H type-like 1; Zinc finger protein 36, C3H1 type-like 1; zinc finger protein, C3H type, 36-like 1

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基因别名: BERG36; BRF1; cMG1; ERF-1; ERF1; RNF162B; TIS11B; ZFP36L1

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UniProt ID: (Human) Q07352

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Entrez Gene ID: (Human) 677

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功能

DNA binding transcription factor activity, sequence-specific DNA binding mRNA binding mRNA 3'-UTR binding protein binding mRNA 3'-UTR AU-rich region binding poly(A) RNA binding metal ion binding 14-3-3 protein binding RNA metabolism protein

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