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产品信息
PA5-52373
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2649923
产品详细信息
Immunogen sequence: PQEYDQLAAK TGLVRTEIVR WFKENRCLLK TGTVKWMEQY QHQPMADDHG YDAVARKATK PMAESPKNGG DVVPQYYKDP KKLCEEDLEK LVTRVKVGSE PAKDCLPAKP SEATSDRSEG SSRDGQGSDE NEESSVVDYV
Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 74%.
靶标信息
Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys(2)-His(2)-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AFP regulator 1; Alpha-fetoprotein regulator 1; Regulator of AFP; transcription factor ZHX2; Zinc finger and homeodomain protein 2; Zinc fingers and homeoboxes protein 2; zinc-fingers and homeoboxes 2
基因别名: AFR1; KIAA0854; RAF; ZHX2
UniProt ID: (Human) Q9Y6X8
Entrez Gene ID: (Human) 22882
