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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MPLCRPEHLM PRASRVPVAA SLPLSHAVIP TQLPSRSGHR PPGRPRRCPK ASCLPPPVGP SSTQTAKRVT MGWPRPGQAL VAVKALLVLS LLQVPAQAVV RAVLEDNSSS VDFADLPALF GVPLAPEGIR GYLMEVKPAN ACHPIEAPRL GNRSLGSIAL IRHYDCTFDL KVLNAQRAGF EAAIVHNVHS DDLVSMTHVY EDLRGQIAIP SVFVSEAASQ DLRVILGCNK SAHALLLPDD PPCHDLGCHP VLTVSWVLGC TLALVVSAFF VLNHLWLWAQ ACCSHRRPVK TSTCQKAQVR TFTWHNDLCA ICLDEYEEGD QLKILPCSHT YHCKCIDPWF SQAPRRSCPV CKQSVAATED SFDSTTYSFR DEDPSLPGHR PPIWAIQVQL RSRRLELLGR ASPHCHCSTT SLEAEYTTVS SAPPEAPGQ
E3 ubiquitin-protein ligase that acts as a negative regulator of NOD2 signaling by mediating ubiquitination and degradation of RIPK2. Also catalyzes ubiquitination and proteasomal degradation of CANX within the endoplasmic reticulum. Could have a role in spermatogenesis (By similarity).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E3 ubiquitin-protein ligase ZNRF4; KOX18; Nixin; RING finger protein 204; RING-type E3 ubiquitin transferase ZNRF4; Zinc/RING finger protein 4; ZNF139; ZNF36
基因别名: RNF204; SPERIZIN; spzn; Ssrzf1; ZNRF4
UniProt ID: (Human) Q8WWF5
Entrez Gene ID: (Human) 148066