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Peptide Sequence: SSSVDFADLP ALFGVPLAPE GIRGYLMEVK PANACHPIEA PRLGNRSLGS IALIRRYDCT FDL
E3 ubiquitin-protein ligase that acts as a negative regulator of NOD2 signaling by mediating ubiquitination and degradation of RIPK2. Also catalyzes ubiquitination and proteasomal degradation of CANX within the endoplasmic reticulum. Could have a role in spermatogenesis (By similarity).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E3 ubiquitin-protein ligase ZNRF4; KOX18; Nixin; RING finger protein 204; RING-type E3 ubiquitin transferase ZNRF4; Zinc/RING finger protein 4; ZNF139; ZNF36
基因别名: RNF204; SPERIZIN; spzn; Ssrzf1; ZNRF4
UniProt ID: (Human) Q8WWF5
Entrez Gene ID: (Human) 148066