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产品信息
PA5-18971
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (KWLDRYRQIRPCTS) corresponding to the C-terminus amino acids of ZRANB1
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_10982110
产品详细信息
This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.
靶标信息
ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. It acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription and may also modulate TNF-alpha signaling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp762P2216; hTrabid; TRAF-binding domain-containing protein; TRAF-binding protein domain; Ubiquitin thioesterase ZRANB1; Zinc finger Ran-binding domain-containing protein 1; zinc finger, RAN-binding domain containing 1
基因别名: TRABID; ZRANB1
UniProt ID: (Human) Q9UGI0
Entrez Gene ID: (Human) 54764
cytoskeleton organization
Wnt signaling pathway
cell migration
regulation of cell morphogenesis
positive regulation of Wnt signaling pathway
protein K29-linked deubiquitination
protein K63-linked deubiquitination
protein deubiquitination involved in ubiquitin-dependent protein catabolic process
protein K33-linked deubiquitination
