Product References
Endothelial Caspase-8 prevents fatal necroptotic hemorrhage caused by commensal bacteria.
Cell death and differentiation
Bader SM,Preston SP,Saliba K,Lipszyc A,Grant ZL,Mackiewicz L,Baldi A,Hempel A,Clark MP,Peiris T,Clow W,Bjelic J,Stutz MD,Arandjelovic P,Teale J,Du F,Coultas L,Murphy JM,Allison CC,Pellegrini M,Samson AL
A-11132 was used in Immunohistochemistry-immunofluorescence to investigate whether endothelial Caspase-8 is also required for cardiovascular patency during adulthood.
Sun Jan 01 00:00:00 EST 2023
7-Ketocholesterol accelerates pancreatic β-cell senescence by inhibiting the SIRT1/CDK4-Rb-E2F1 signaling pathway.
Islets
Zhu Q,Wang W,Wu N,He S,Lin X,Zhang W,Zhou J
A-11132 was used in Immunocytochemistry to investigate the role of 7-KC in pancreatic β-cell senescence and its underlying molecular mechanism in MIN6 cells.
Sun Dec 31 00:00:00 EST 2023
7-Ketocholesterol accelerates pancreatic β-cell senescence by inhibiting the SIRT1/CDK4-Rb-E2F1 signaling pathway.
Islets
Zhu Q,Wang W,Wu N,He S,Lin X,Zhang W,Zhou J
A-11132 was used in Immunocytochemistry to investigate the role of 7-KC in pancreatic β-cell senescence and its underlying molecular mechanism in MIN6 cells.
Sun Dec 31 00:00:00 EST 2023
Cardiac Troponin I-Interacting Kinase Affects Cardiomyocyte S-Phase Activity but Not Cardiomyocyte Proliferation.
Circulation
Reuter SP,Soonpaa MH,Field D,Simpson E,Rubart-von der Lohe M,Lee HK,Sridhar A,Ware SM,Green N,Li X,Ofner S,Marchuk DA,Wollert KC,Field LJ
A-11132 was used in Immunohistochemistry-immunofluorescence to indicate that Tnni3k expression increases the level of cardiomyocyte S-phase activity after injury.
Tue Jan 10 00:00:00 EST 2023
Transcriptional and epigenetic decoding of the microglial aging process.
Nature aging
Li X,Li Y,Jin Y,Zhang Y,Wu J,Xu Z,Huang Y,Cai L,Gao S,Liu T,Zeng F,Wang Y,Wang W,Yuan TF,Tian H,Shu Y,Guo F,Lu W,Mao Y,Mei X,Rao Y,Peng B
A-11132 was used in Immunohistochemistry (Frozen) to map the transcriptional and epigenetic profiles of microglia from 3- to 24-month-old mice.
Sun Oct 01 00:00:00 EDT 2023
P2RY14 cAMP signaling regulates Schwann cell precursor self-renewal, proliferation, and nerve tumor initiation in a mouse model of neurofibromatosis.
eLife
Patritti Cram J,Wu J,Coover RA,Rizvi TA,Chaney KE,Ravindran R,Cancelas JA,Spinner RJ,Ratner N
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunohistochemistry
Mon Mar 21 00:00:00 EDT 2022
Nebulized mRNA-Encoded Antibodies Protect Hamsters from SARS-CoV-2 Infection.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Vanover D,Zurla C,Peck HE,Orr-Burks N,Joo JY,Murray J,Holladay N,Hobbs RA,Jung Y,Chaves LCS,Rotolo L,Lifland AW,Olivier AK,Li D,Saunders KO,Sempowski GD,Crowe JE,Haynes BF,Lafontaine ER,Hogan RJ,Santangelo PJ
A-11132 was used in Immunohistochemistry (Paraffin) to support the use of nebulizer-based mRNA expression of neutralizing antibodies as a new paradigm for mitigating respiratory virus infections.
Thu Dec 01 00:00:00 EST 2022
Biasing the conformation of ELMO2 reveals that myoblast fusion can be exploited to improve muscle regeneration.
Nature communications
Tran V,Nahlé S,Robert A,Desanlis I,Killoran R,Ehresmann S,Thibault MP,Barford D,Ravichandran KS,Sauvageau M,Smith MJ,Kmita M,Côté JF
A-11132 was used in Immunohistochemistry-immunofluorescence to analyze the contribution of the DOCK1-interacting ELMO scaffold proteins to myoblast fusion.
Fri Nov 18 00:00:00 EST 2022
Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells.
Neuron
Franjic D,Skarica M,Ma S,Arellano JI,Tebbenkamp ATN,Choi J,Xu C,Li Q,Morozov YM,Andrijevic D,Vrselja Z,Spajic A,Santpere G,Li M,Zhang S,Liu Y,Spurrier J,Zhang L,Gudelj I,Rapan L,Takahashi H,Huttner A,Fan R,Strittmatter SM,Sousa AMM,Rakic P,Sestan N
A-11132 was used in Immunohistochemistry to investigate neurogenic potential and cellular diversity by profiling single-nucleus transcriptomes in five hippocampal-entorhinal subregions in humans, macaques, and pigs.
Wed Feb 02 00:00:00 EST 2022
A remarkable adaptive paradigm of heart performance and protection emerges in response to marked cardiac-specific overexpression of ADCY8.
eLife
Tarasov KV,Chakir K,Riordon DR,Lyashkov AE,Ahmet I,Perino MG,Silvester AJ,Zhang J,Wang M,Lukyanenko YO,Qu JH,Barrera MC,Juhaszova M,Tarasova YS,Ziman B,Telljohann R,Kumar V,Ranek M,Lammons J,Bychkov R,de Cabo R,Jun S,Keceli G,Gupta A,Yang D,Aon MA,Adamo L,Morrell CH,Otu W,Carroll C,Chambers S,Paolocci N,Huynh T,Pacak K,Weiss R,Field L,Sollott SJ,Lakatta EG
A-11132 was used in Immunohistochemistry-immunofluorescence to show that TGAC8 mice show classical cardiac hypertrophy markers were absent in TGAC8, and that total left ventricular (LV) mass was not increased: a reduced LV cavity volume in TGAC8 was encased by thicker LV walls harboring an increased number of small cardiac myocytes, and a network of small interstitial proliferative non-cardiac myocytes compared to wild type (WT) littermates compared to wild type littermates.
Wed Dec 14 00:00:00 EST 2022
Both Specific Endothelial and Proximal Tubular Adam17 Deletion Protect against Diabetic Nephropathy.
International journal of molecular sciences
Palau V,Nugraha B,Benito D,Pascual J,Emmert MY,Hoerstrup SP,Riera M,Soler MJ
A-11132 was used in Immunohistochemistry (Paraffin) to to investigate if Adam17 deletion either in the endothelial or the tubular cells mitigates kidney injury in the diabetic mice by targeting different pathways.
Mon May 24 00:00:00 EDT 2021
Both Specific Endothelial and Proximal Tubular Adam17 Deletion Protect against Diabetic Nephropathy.
International journal of molecular sciences
Palau V,Nugraha B,Benito D,Pascual J,Emmert MY,Hoerstrup SP,Riera M,Soler MJ
A-11132 was used in Immunohistochemistry (Paraffin) to to investigate if Adam17 deletion either in the endothelial or the tubular cells mitigates kidney injury in the diabetic mice by targeting different pathways.
Mon May 24 00:00:00 EDT 2021
Both Specific Endothelial and Proximal Tubular Adam17 Deletion Protect against Diabetic Nephropathy.
International journal of molecular sciences
Palau V,Nugraha B,Benito D,Pascual J,Emmert MY,Hoerstrup SP,Riera M,Soler MJ
A-11132 was used in Immunohistochemistry (Paraffin) to to investigate if Adam17 deletion either in the endothelial or the tubular cells mitigates kidney injury in the diabetic mice by targeting different pathways.
Mon May 24 00:00:00 EDT 2021
Hedgehog signaling and Tre1 regulate actin dynamics through PI(4,5)P2 to direct migration of Drosophila embryonic germ cells.
Cell reports
Kim JH,Hanlon CD,Vohra S,Devreotes PN,Andrew DJ
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunocytochemistry
Tue Mar 02 00:00:00 EST 2021
Hedgehog signaling and Tre1 regulate actin dynamics through PI(4,5)P2 to direct migration of Drosophila embryonic germ cells.
Cell reports
Kim JH,Hanlon CD,Vohra S,Devreotes PN,Andrew DJ
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunocytochemistry
Tue Mar 02 00:00:00 EST 2021
Transcription Factor β-Catenin Plays a Key Role in Fluid Flow Shear Stress-Mediated Glomerular Injury in Solitary Kidney.
Cells
Srivastava T,Heruth DP,Duncan RS,Rezaiekhaligh MH,Garola RE,Priya L,Zhou J,Boinpelly VC,Novak J,Ali MF,Joshi T,Alon US,Jiang Y,McCarthy ET,Savin VJ,Sharma R,Johnson ML,Sharma M
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunocytochemistry
Wed May 19 00:00:00 EDT 2021
Multiscale analysis reveals that diet-dependent midgut plasticity emerges from alterations in both stem cell niche coupling and enterocyte size.
eLife
Bonfini A,Dobson AJ,Duneau D,Revah J,Liu X,Houtz P,Buchon N
A-11132 was used in Immunohistochemistry to clarify the complex relationships between nutrition, epithelial dynamics, and cell size, and reveal a new mode of plastic, diet-dependent organ resizing.
Thu Sep 23 00:00:00 EDT 2021
Accumulation of saposin in dystrophic neurites is linked to impaired lysosomal functions in Alzheimer's disease brains.
Molecular neurodegeneration
Sharoar MG,Palko S,Ge Y,Saido TC,Yan R
A-11132 was used in Immunohistochemistry to indicate that lysosomal functions are impaired by being entrapped in DNs early during plaque growth, and this may viciously facilitate growth of amyloid plaques.
Fri Jul 02 00:00:00 EDT 2021
Magnesium and Calcium Homeostasis Depend on KCTD1 Function in the Distal Nephron.
Cell reports
Marneros AG
A-11132 was used in Immunohistochemistry to conclude that KCTD1 regulates urinary reabsorption of Mg2+ and Ca2+ by inducing expression of NCC in DCTs and NKCC2/claudin-16/-19 in TALs.
Tue Jan 12 00:00:00 EST 2021
R7 photoreceptor axon targeting depends on the relative levels of lost and found expression in R7 and its synaptic partners.
eLife
Douthit J,Hairston A,Lee G,Morrison CA,Holguera I,Treisman JE
A-11132 was used in Immunohistochemistry-immunofluorescence to show that the Drosophila CUB-LDL protein Lost and found (Loaf) is required in the UV-sensitive R7 photoreceptor for normal axon targeting only when Loaf is also present in its synaptic partners.
Tue May 18 00:00:00 EDT 2021
Functional interpretation of ATAD3A variants in neuro-mitochondrial phenotypes.
Genome medicine
Yap ZY,Park YH,Wortmann SB,Gunning AC,Ezer S,Lee S,Duraine L,Wilichowski E,Wilson K,Mayr JA,Wagner M,Li H,Kini U,Black ED,Monaghan KG,Lupski JR,Ellard S,Westphal DS,Harel T,Yoon WH
A-11132 was used in Immunohistochemistry to expand the allelic spectrum of ATAD3A variants and exemplify the use of a functional assay in Drosophila to aid variant interpretation.
Mon Apr 12 00:00:00 EDT 2021
Pathogenic SREK1 decrease in Huntington's disease lowers TAF1 mimicking X-linked dystonia parkinsonism.
Brain : a journal of neurology
Hernández IH,Cabrera JR,Santos-Galindo M,Sánchez-Martín M,Domínguez V,García-Escudero R,Pérez-Álvarez MJ,Pintado B,Lucas JJ
A-11132 was used in Immunohistochemistry to demonstrate that altered RNA processing upon SREK1 dysregulation plays a key role in Huntington's disease pathogensis, with TAF1 as a likely determinant of selective vulnerability of the striatum in multiple neurological disorders.
Wed Jul 01 00:00:00 EDT 2020
AP-2β/KCTD1 Control Distal Nephron Differentiation and Protect against Renal Fibrosis.
Developmental cell
Marneros AG
A-11132 was used in Immunohistochemistry to show that the transcription factor AP-2β is required for the differentiation of distal tubule precursors into early stage distal convoluted tubules during nephrogenesis.
Mon Aug 10 00:00:00 EDT 2020
Transduction Efficiency of Adeno-Associated Virus Serotypes After Local Injection in Mouse and Human Skeletal Muscle.
Human gene therapy
Muraine L,Bensalah M,Dhiab J,Cordova G,Arandel L,Marhic A,Chapart M,Vasseur S,Benkhelifa-Ziyyat S,Bigot A,Butler-Browne G,Mouly V,Negroni E,Trollet C
A-11132 was used in Western Blotting to demonstrate for the first time that the human muscle xenograft can be used to evaluate AAV-based therapeutical approaches in a human context.
Sat Feb 01 00:00:00 EST 2020
Restriction on self-renewing asymmetric division is coupled to terminal asymmetric division in the Drosophila CNS.
PLoS genetics
Gaziova I,Gazi M,Mar J,Bhat KM
A-11132 was used in Immunohistochemistry-wholemount to reveal a Mid-regulated pathway that restricts the self-renewing asymmetric division potential of cells via inhibiting cyclin E and facilitating their exit from cell cycle.
Tue Sep 01 00:00:00 EDT 2020
Restriction on self-renewing asymmetric division is coupled to terminal asymmetric division in the Drosophila CNS.
PLoS genetics
Gaziova I,Gazi M,Mar J,Bhat KM
A-11132 was used in Immunohistochemistry-wholemount to reveal a Mid-regulated pathway that restricts the self-renewing asymmetric division potential of cells via inhibiting cyclin E and facilitating their exit from cell cycle.
Tue Sep 01 00:00:00 EDT 2020
In Vivo Cell Fate Tracing Provides No Evidence for Mesenchymal to Epithelial Transition in Adult Fallopian Tube and Uterus.
Cell reports
Ghosh A,Syed SM,Kumar M,Carpenter TJ,Teixeira JM,Houairia N,Negi S,Tanwar PS
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunohistochemistry (Paraffin)
Tue May 12 00:00:00 EDT 2020
In Vivo Cell Fate Tracing Provides No Evidence for Mesenchymal to Epithelial Transition in Adult Fallopian Tube and Uterus.
Cell reports
Ghosh A,Syed SM,Kumar M,Carpenter TJ,Teixeira JM,Houairia N,Negi S,Tanwar PS
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunohistochemistry (Paraffin)
Tue May 12 00:00:00 EDT 2020
In Vivo Cell Fate Tracing Provides No Evidence for Mesenchymal to Epithelial Transition in Adult Fallopian Tube and Uterus.
Cell reports
Ghosh A,Syed SM,Kumar M,Carpenter TJ,Teixeira JM,Houairia N,Negi S,Tanwar PS
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunohistochemistry (Paraffin)
Tue May 12 00:00:00 EDT 2020
Lola regulates Drosophila adult midgut homeostasis via non-canonical hippo signaling.
eLife
Hao X,Wang S,Lu Y,Yu W,Li P,Jiang D,Guo T,Li M,Li J,Xu J,Wu W,Ho MS,Zhang L
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunocytochemistry
Tue Jan 14 00:00:00 EST 2020
Insulin synthesized in the paraventricular nucleus of the hypothalamus regulates pituitary growth hormone production.
JCI insight
Lee J,Kim K,Cho JH,Bae JY,O'Leary TP,Johnson JD,Bae YC,Kim EK
A-11132 was used in Immunohistochemistry to investigate the distribution and functions of insulin-expressing cells in the mouse hypothalamus.
Thu Aug 20 00:00:00 EDT 2020
Fat Body p53 Regulates Systemic Insulin Signaling and Autophagy under Nutrient Stress via Drosophila Upd2 Repression.
Cell reports
Ingaramo MC,Sánchez JA,Perrimon N,Dekanty A
A-11132 was used in Immunohistochemistry to demonstrate an essential role for the AMPK-Dmp53 axis in nutrient stress responses and expand the concept that adipose tissue acts as a sensing organ that orchestrates systemic adaptation to nutrient status.
Tue Oct 27 00:00:00 EDT 2020
Targeting VE-PTP phosphatase protects the kidney from diabetic injury.
The Journal of experimental medicine
Carota IA,Kenig-Kozlovsky Y,Onay T,Scott R,Thomson BR,Souma T,Bartlett CS,Li Y,Procissi D,Ramirez V,Yamaguchi S,Tarjus A,Tanna CE,Li C,Eremina V,Vestweber D,Oladipupo SS,Breyer MD,Quaggin SE
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunocytochemistry
Mon Apr 01 00:00:00 EDT 2019
Targeting VE-PTP phosphatase protects the kidney from diabetic injury.
The Journal of experimental medicine
Carota IA,Kenig-Kozlovsky Y,Onay T,Scott R,Thomson BR,Souma T,Bartlett CS,Li Y,Procissi D,Ramirez V,Yamaguchi S,Tarjus A,Tanna CE,Li C,Eremina V,Vestweber D,Oladipupo SS,Breyer MD,Quaggin SE
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunocytochemistry
Mon Apr 01 00:00:00 EDT 2019
ELFN2 is a postsynaptic cell adhesion molecule with essential roles in controlling group III mGluRs in the brain and neuropsychiatric behavior.
Molecular psychiatry
Dunn HA,Zucca S,Dao M,Orlandi C,Martemyanov KA
A-11132 was used in Immunohistochemistry to demonstrate that extracellular transsynaptic scaffolding by ELFN2 in the brain is a cardinal organizational feature of group III mGluRs essential for their signaling properties and brain function.
Sun Dec 01 00:00:00 EST 2019
ELFN2 is a postsynaptic cell adhesion molecule with essential roles in controlling group III mGluRs in the brain and neuropsychiatric behavior.
Molecular psychiatry
Dunn HA,Zucca S,Dao M,Orlandi C,Martemyanov KA
A-11132 was used in Immunohistochemistry to demonstrate that extracellular transsynaptic scaffolding by ELFN2 in the brain is a cardinal organizational feature of group III mGluRs essential for their signaling properties and brain function.
Sun Dec 01 00:00:00 EST 2019
Cellular labeling of endogenous retrovirus replication (CLEVR) reveals de novo insertions of the gypsy retrotransposable element in cell culture and in both neurons and glial cells of aging fruit flies.
PLoS biology
Chang YH,Keegan RM,Prazak L,Dubnau J
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunofluorescence
Wed May 01 00:00:00 EDT 2019
Cellular labeling of endogenous retrovirus replication (CLEVR) reveals de novo insertions of the gypsy retrotransposable element in cell culture and in both neurons and glial cells of aging fruit flies.
PLoS biology
Chang YH,Keegan RM,Prazak L,Dubnau J
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunofluorescence
Wed May 01 00:00:00 EDT 2019
Lar maintains the homeostasis of the hematopoietic organ in Drosophila by regulating insulin signaling in the niche.
Development (Cambridge, England)
Kaur H,Sharma SK,Mandal S,Mandal L
A-11132 was used in Immunohistochemistry to study if Lar physically associates with InR and serves as a negative regulator for insulin signaling in Drosophila larval hematopoietic niche.
Mon Dec 23 00:00:00 EST 2019
CARM1 regulates senescence during airway epithelial cell injury in COPD pathogenesis.
American journal of physiology. Lung cellular and molecular physiology
Sarker RSJ,Conlon TM,Morrone C,Srivastava B,Konyalilar N,Verleden SE,Bayram H,Fehrenbach H,Yildirim AÖ
A-11132 was used in Immunohistochemistry (Paraffin) to support airway repair and regeneration in chronic obstructive pulmonary disease.
Fri Nov 01 00:00:00 EDT 2019
SALM4 regulates angiogenic functions in endothelial cells through VEGFR2 phosphorylation at Tyr1175.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Kim DY,Park JA,Kim Y,Noh M,Park S,Lie E,Kim E,Kim YM,Kwon YG
A-11132 was used in Immunohistochemistry-immunofluorescence to report that synaptic adhesion-like molecule 4 regulates a specific VEGFR2 phosphorylation site.
Sun Sep 01 00:00:00 EDT 2019
Eiger/TNFα-mediated Dilp8 and ROS production coordinate intra-organ growth in Drosophila.
PLoS genetics
Sanchez JA,Mesquita D,Ingaramo MC,Ariel F,Milán M,Dekanty A
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunohistochemistry
Thu Aug 01 00:00:00 EDT 2019
Claudin-12 is not required for blood-brain barrier tight junction function.
Fluids and barriers of the CNS
Castro Dias M,Coisne C,Baden P,Enzmann G,Garrett L,Becker L,Hölter SM,Hrabě de Angelis M,Deutsch U,Engelhardt B
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunofluorescence
Thu Sep 12 00:00:00 EDT 2019
Claudin-12 is not required for blood-brain barrier tight junction function.
Fluids and barriers of the CNS
Castro Dias M,Coisne C,Baden P,Enzmann G,Garrett L,Becker L,Hölter SM,Hrabě de Angelis M,Deutsch U,Engelhardt B
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunofluorescence
Thu Sep 12 00:00:00 EDT 2019
Cellular properties of intrinsically photosensitive retinal ganglion cells during postnatal development.
Neural development
Lucas JA,Schmidt TM
A-11132 was used in Immunohistochemistry to show that ipRGC subtypes are distinguishable from each other early in postnatal development.
Fri Aug 30 00:00:00 EDT 2019
Genetic Lineage Tracing of Biliary Epithelial Cells.
Methods in molecular biology (Clifton, N.J.)
Rubio-Tomás T,Aguilar-Bravo B,Sancho-Bru P
A-11132 was used in Immunohistochemistry to suggest possible readouts to assess BECs fate based on immunofluorescence analysis.
Tue Jun 11 00:00:00 EDT 2019
A Novel Birthdate-Labeling Method Reveals Segregated Parallel Projections of Mitral and External Tufted Cells in the Main Olfactory System.
eNeuro
Hirata T,Shioi G,Abe T,Kiyonari H,Kato S,Kobayashi K,Mori K,Kawasaki T
A-11132 was used in Immunohistochemistry to develop a Cre-loxP-based method that allows for birthdate-specific labeling of cell bodies and their axon projections in mice.
Wed Jun 03 00:00:00 EDT 2020
The WT1-like transcription factor Klumpfuss maintains lineage commitment of enterocyte progenitors in the Drosophila intestine.
Nature communications
Korzelius J,Azami S,Ronnen-Oron T,Koch P,Baldauf M,Meier E,Rodriguez-Fernandez IA,Groth M,Sousa-Victor P,Jasper H
A-11132 was used in Immunohistochemistry to show transcription factor Klumpfuss can suppress the action of proneural gene Scute to influence enteroendocrine fate.
Wed Sep 11 00:00:00 EDT 2019
Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing.
Nature
Parras A,Anta H,Santos-Galindo M,Swarup V,Elorza A,Nieto-González JL,Picó S,Hernández IH,Díaz-Hernández JI,Belloc E,Rodolosse A,Parikshak NN,Peñagarikano O,Fernández-Chacón R,Irimia M,Navarro P,Geschwind DH,Méndez R,Lucas JJ
A-11132 was used in Immunohistochemistry to study the role of cytoplasmic polyadenylation element binding protein 4 in the regulation of autism spectrum disorder risk genes.
Wed Aug 01 00:00:00 EDT 2018
Deletion of Tmtc4 activates the unfolded protein response and causes postnatal hearing loss.
The Journal of clinical investigation
Li J,Akil O,Rouse SL,McLaughlin CW,Matthews IR,Lustig LR,Chan DK,Sherr EH
A-11132 was used in Immunohistochemistry to identify a novel mechanism for hearing impairment, highlighting a potential treatment approach for a broad range of human hearing loss disorders.
Thu Nov 01 00:00:00 EDT 2018
FGF controls epithelial-mesenchymal transitions during gastrulation by regulating cell division and apicobasal polarity.
Development (Cambridge, England)
Sun J,Stathopoulos A
A-11132 was used in Immunohistochemistry to highlight the supportive role of fibroblast growth factor during mesoderm cell development to ensure collective cell movements and proper differentiation.
Mon Oct 01 00:00:00 EDT 2018
Insulin-Deficient Mouse β-Cells Do Not Fully Mature but Can Be Remedied Through Insulin Replacement by Islet Transplantation.
Endocrinology
Ramzy A,Mojibian M,Kieffer TJ
A-11132 was used in Immunohistochemistry-immunofluorescence to suggest that tightly regulated glycemia, insulin species, or other islet factors are necessary for Β-cell maturation.
Mon Jan 01 00:00:00 EST 2018
Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control.
Biology of sex differences
Coleman JLJ,Mouat MA,Wu J,Jancovski N,Bassi JK,Chan AY,Humphreys DT,Mrad N,Yu ZY,Ngo T,Iismaa S,Dos Remedios CG,Feneley MP,Allen AM,Graham RM,Smith NJ
A-11132 was used in Western Blotting to investigate the role of GPR37L1 in blood pressure homeostasis.
Fri Apr 06 00:00:00 EDT 2018
MifM-instructed translation arrest involves nascent chain interactions with the exterior as well as the interior of the ribosome.
Scientific reports
Fujiwara K,Ito K,Chiba S
A-11132 was used in Western Blotting to study the roles played by N-terminal regions of Bacillus subtilis MifM in the regulation of translational elongation arrest.
Mon Jul 09 00:00:00 EDT 2018
MET Signaling Mediates Intestinal Crypt-Villus Development, Regeneration, and Adenoma Formation and Is Promoted by Stem Cell CD44 Isoforms.
Gastroenterology
Joosten SPJ,Zeilstra J,van Andel H,Mijnals RC,Zaunbrecher J,Duivenvoorden AAM,van de Wetering M,Clevers H,Spaargaren M,Pals ST
A-11132 was used in Immunohistochemistry to investigate how MET signalling, and its interaction with CD44 affects intestinal homeostasis, regeneration, and adenoma formation in mini-gut organoids and mice.
Sun Oct 01 00:00:00 EDT 2017
Prevention of medulla neuron dedifferentiation by Nerfin-1 requires inhibition of Notch activity.
Development (Cambridge, England)
Xu J,Hao X,Yin MX,Lu Y,Jin Y,Xu J,Ge L,Wu W,Ho M,Yang Y,Zhao Y,Zhang L
A-11132 was used in Immunohistochemistry to conclude that Nerfin-1 represses Notch activity in medulla neurons and prevents them from dedifferentiation.
Sat Apr 15 00:00:00 EDT 2017
The Transcription Factor Foxg1 Promotes Optic Fissure Closure in the Mouse by Suppressing Wnt8b in the Nasal Optic Stalk.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Smith R,Huang YT,Tian T,Vojtasova D,Mesalles-Naranjo O,Pollard SM,Pratt T,Price DJ,Fotaki V
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunohistochemistry
Wed Aug 16 00:00:00 EDT 2017
Osteoclast stimulation factor 1 (Ostf1) KNOCKOUT increases trabecular bone mass in mice.
Mammalian genome : official journal of the International Mammalian Genome Society
Vermeren M,Lyraki R,Wani S,Airik R,Albagha O,Mort R,Hildebrandt F,Hurd T
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Western Blot
Fri Dec 01 00:00:00 EST 2017
Netrin-1 Derived from the Ventricular Zone, but not the Floor Plate, Directs Hindbrain Commissural Axons to the Ventral Midline.
Scientific reports
Yamauchi K,Yamazaki M,Abe M,Sakimura K,Lickert H,Kawasaki T,Murakami F,Hirata T
A-11132 was used in Immunohistochemistry to suggest that ventricular zone-derived netrin-1 directs commissural axons to the ventral midline by its local actions.
Wed Sep 20 00:00:00 EDT 2017
Co-delivery of indoleamine 2,3-dioxygenase prevents loss of expression of an antigenic transgene in dystrophic mouse muscles.
Gene therapy
Sharma D,Al-Khalidi R,Edgar S,An Q,Wang Y,Young C,Nowis D,Gorecki DC
A-11132 was used in Western Blotting to indicate that co-expression of genes encoding immunomodulatory enzymes controlling kynurenine pathways provide a viable strategy for preventing loss of transgenes targeted into dystrophic muscles with pre-existing inflammation.
Wed Feb 01 00:00:00 EST 2017
Co-delivery of indoleamine 2,3-dioxygenase prevents loss of expression of an antigenic transgene in dystrophic mouse muscles.
Gene therapy
Sharma D,Al-Khalidi R,Edgar S,An Q,Wang Y,Young C,Nowis D,Gorecki DC
A-11132 was used in Western Blotting to indicate that co-expression of genes encoding immunomodulatory enzymes controlling kynurenine pathways provide a viable strategy for preventing loss of transgenes targeted into dystrophic muscles with pre-existing inflammation.
Wed Feb 01 00:00:00 EST 2017
Increased VEGF-A promotes multiple distinct aging diseases of the eye through shared pathomechanisms.
EMBO molecular medicine
Marneros AG
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunofluorescence
Tue Mar 01 00:00:00 EST 2016
Taiman acts as a coactivator of Yorkie in the Hippo pathway to promote tissue growth and intestinal regeneration.
Cell discovery
Wang C,Yin MX,Wu W,Dong L,Wang S,Lu Y,Xu J,Wu W,Li S,Zhao Y,Zhang L
A11132 was used in immunohistochemistry to study how Taiman and Yorkie interact to regulate intestinal stem cell proliferation
Wed Jul 27 00:00:00 EDT 2016
Lineage mapping identifies molecular and architectural similarities between the larval and adult Drosophila central nervous system.
eLife
Lacin H,Truman JW
A-11132 was used in immunohistochemistry to study molecular and architectural differences by lineage m apping between larval and adult drosophila central nervous system
Tue Mar 15 00:00:00 EDT 2016
Transcriptome Profiling Identifies Multiplexin as a Target of SAGA Deubiquitinase Activity in Glia Required for Precise Axon Guidance During Drosophila Visual Development.
G3 (Bethesda, Md.)
Ma J,Brennan KJ,D'Aloia MR,Pascuzzi PE,Weake VM
A-11132 was used in immunohistochemistry use Drosophila to identify the gene targets of SAGA deubiquitinase activity in glia
Tue Aug 09 00:00:00 EDT 2016
p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration.
Nature
Zuo W,Zhang T,Wu DZ,Guan SP,Liew AA,Yamamoto Y,Wang X,Lim SJ,Vincent M,Lessard M,Crum CP,Xian W,McKeon F
A-11132 was used in immunohistochemistry to investigate how DASC(p63/Krt5) regulates regeneration of tissue after influenza-induced lung damage.
Thu Jan 29 00:00:00 EST 2015
A novel fragile X syndrome mutation reveals a conserved role for the carboxy-terminus in FMRP localization and function.
EMBO molecular medicine
Okray Z,de Esch CE,Van Esch H,Devriendt K,Claeys A,Yan J,Verbeeck J,Froyen G,Willemsen R,de Vrij FM,Hassan BA
A-11132 was used in immunohistochemistry to identify and characterize a novel FMR1 mutation.
Wed Apr 01 00:00:00 EDT 2015
Coordinate control of terminal dendrite patterning and dynamics by the membrane protein Raw.
Development (Cambridge, England)
Lee J,Peng Y,Lin WY,Parrish JZ
A-11132 was used in immunohistochemistry to assess the developmental origin of subcompartments in axons and dendrites
Thu Jan 01 00:00:00 EST 2015
Characterization of Panglial Gap Junction Networks in the Thalamus, Neocortex, and Hippocampus Reveals a Unique Population of Glial Cells.
Cerebral cortex (New York, N.Y. : 1991)
Griemsmann S,Höft SP,Bedner P,Zhang J,von Staden E,Beinhauer A,Degen J,Dublin P,Cope DW,Richter N,Crunelli V,Jabs R,Willecke K,Theis M,Seifert G,Kettenmann H,Steinhäuser C
A-11132 was used in immunohistochemistry to describe the formation of coupled networks between astrocytes and oligodendrocytes in the murine ventrobasal thalamus and compare these associations with those found in the hippocampus and cortex.
Thu Oct 01 00:00:00 EDT 2015
Characterization of Antibodies to Products of Proinsulin Processing Using Immunofluorescence Staining of Pancreas in Multiple Species.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Asadi A,Bruin JE,Kieffer TJ
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunofluorescence
Sat Aug 01 00:00:00 EDT 2015
Differential Effects of Axin2 Deficiency on the Fibrogenic and Regenerative Response in Livers of Bile Duct-Ligated Mice.
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes
Abshagen K,Senne M,Genz B,Thomas M,Vollmar B
A-11132 was used in immunohistochemistry to test if Axin2 deficiency promotes fibrogenesis
Tue Dec 01 00:00:00 EST 2015
Rejuvenation of the muscle stem cell population restores strength to injured aged muscles.
Nature medicine
Cosgrove BD,Gilbert PM,Porpiglia E,Mourkioti F,Lee SP,Corbel SY,Llewellyn ME,Delp SL,Blau HM
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunofluorescence
Sat Mar 01 00:00:00 EST 2014
Antagonistic regulation of p57kip2 by Hes/Hey downstream of Notch signaling and muscle regulatory factors regulates skeletal muscle growth arrest.
Development (Cambridge, England)
Zalc A,Hayashi S,Auradé F,Bröhl D,Chang T,Mademtzoglou D,Mourikis P,Yao Z,Cao Y,Birchmeier C,Relaix F
A-11132 was used in Chromatin immunoprecipitation to investigate how the interactions between p21(cip1) and p57(kip2), the Notch pathway, and myogenic regulatory factors orchestrate the proliferation, specification, and differentiation of muscle progenitor cells.
Tue Jul 01 00:00:00 EDT 2014
The RNA-binding protein ELAV regulates Hox RNA processing, expression and function within the Drosophila nervous system.
Development (Cambridge, England)
Rogulja-Ortmann A,Picao-Osorio J,Villava C,Patraquim P,Lafuente E,Aspden J,Thomsen S,Technau GM,Alonso CR
A-11132 was used in immunohistochemistry to explore how RNA processing regulates Hox genes and development of the central nervous system.
Thu May 01 00:00:00 EDT 2014
Progressive dysfunction of the retinal pigment epithelium and retina due to increased VEGF-A levels.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Ablonczy Z,Dahrouj M,Marneros AG
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunofluorescence
Thu May 01 00:00:00 EDT 2014
Progressive dysfunction of the retinal pigment epithelium and retina due to increased VEGF-A levels.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Ablonczy Z,Dahrouj M,Marneros AG
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunofluorescence
Thu May 01 00:00:00 EDT 2014
Kdm3a lysine demethylase is an Hsp90 client required for cytoskeletal rearrangements during spermatogenesis.
Molecular biology of the cell
Kasioulis I,Syred HM,Tate P,Finch A,Shaw J,Seawright A,Fuszard M,Botting CH,Shirran S,Adams IR,Jackson IJ,van Heyningen V,Yeyati PL
A-11132 was used in western blot to study how Kdm3a and Hsp90 interact to regulate cytoskeletal components.
Tue Apr 01 00:00:00 EDT 2014
Cited2 is required in trophoblasts for correct placental capillary patterning.
Developmental biology
Moreau JL,Artap ST,Shi H,Chapman G,Leone G,Sparrow DB,Dunwoodie SL
A-11132 was used in immunohistochemistry to study the role of CITED2 in embryogenesis
Fri Aug 01 00:00:00 EDT 2014
Ephrin-mediated restriction of ERK1/2 activity delimits the number of pigment cells in the Ciona CNS.
Developmental biology
Haupaix N,Abitua PB,Sirour C,Yasuo H,Levine M,Hudson C
A-11132 was used in immunohistochemistry to determine the cell lineage of the pigment cells in Ciona intestinalis embryos.
Wed Oct 01 00:00:00 EDT 2014
Estrogen-related receptor γ serves a role in blood pressure homeostasis during pregnancy.
Molecular endocrinology (Baltimore, Md.)
Luo Y,Kumar P,Chen CC,Latham J,Wang L,Tudela C,Alexander JM,Shelton JM,McKown L,Mendelson CR
A-11132 was used in immunohistochemistry - paraffin section to determine the functional role for ERRgamma during pregnancy.
Sun Jun 01 00:00:00 EDT 2014
Estrogen-related receptor γ serves a role in blood pressure homeostasis during pregnancy.
Molecular endocrinology (Baltimore, Md.)
Luo Y,Kumar P,Chen CC,Latham J,Wang L,Tudela C,Alexander JM,Shelton JM,McKown L,Mendelson CR
A-11132 was used in immunohistochemistry - paraffin section to determine the functional role for ERRgamma during pregnancy.
Sun Jun 01 00:00:00 EDT 2014
Recombinant neuregulin 1 does not activate cardiomyocyte DNA synthesis in normal or infarcted adult mice.
PloS one
Reuter S,Soonpaa MH,Firulli AB,Chang AN,Field LJ
A-11132 was used in Immunocytochemistry to indicate that neuregulin 1Β1 treatment does not increase cardiomyocyte DNA synthesis in normal or infarcted adult mouse hearts.
Mon Oct 26 00:00:00 EDT 2015
Evidence against a role for β-arrestin1 in STAT1 dephosphorylation and the inhibition of interferon-γ signaling.
Molecular cell
Pelzel C,Begitt A,Wenta N,Vinkemeier U
A-11132 was used in western blot to test the impact of β-arrestin on STAT activity.
Thu Apr 11 00:00:00 EDT 2013
Macrophages are essential for the early wound healing response and the formation of a fibrovascular scar.
The American journal of pathology
He L,Marneros AG
A-11132 was used in immunohistochemistry to identify the role of macrophages in wound healing and fibrovascular scar production.
Sat Jun 01 00:00:00 EDT 2013
Deletion of integrin-linked kinase from neural crest cells in mice results in aortic aneurysms and embryonic lethality.
Disease models & mechanisms
Arnold TD,Zang K,Vallejo-Illarramendi A
A-11132 was used in immunohistochemistry - frozen section to investigate the role of Ilk in neural crest cell morphogenesis.
Sun Sep 01 00:00:00 EDT 2013
Psychiatric disorder-related abnormal behavior and habenulointerpeduncular pathway defects in Wnt1-cre and Wnt1-GAL4 double transgenic mice.
Journal of neurochemistry
Nakajima M,Mori H,Nishikawa C,Tsuruta M,Okuyama S,Furukawa Y
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunohistochemistry
Tue Jan 01 00:00:00 EST 2013
Psychiatric disorder-related abnormal behavior and habenulointerpeduncular pathway defects in Wnt1-cre and Wnt1-GAL4 double transgenic mice.
Journal of neurochemistry
Nakajima M,Mori H,Nishikawa C,Tsuruta M,Okuyama S,Furukawa Y
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunohistochemistry
Tue Jan 01 00:00:00 EST 2013
A comparative study of axon-surrounding cells in the two nasal nerve tracts from mouse olfactory epithelium and vomeronasal organ.
Brain research
Nakajima M,Tsuruta M,Mori H,Nishikawa C,Okuyama S,Furukawa Y
A-11132 was used in immunohistochemistry - frozen section to compared the expression patterns of marker proteins in the two nasal nerve tracts.
Fri Mar 29 00:00:00 EDT 2013
Osteoblast and osteocyte-specific loss of Connexin43 results in delayed bone formation and healing during murine fracture healing.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Loiselle AE,Paul EM,Lewis GS,Donahue HJ
A-11132 was used in immunohistochemistry - paraffin section to determine the role of connexin 43 in fracture healing.
Tue Jan 01 00:00:00 EST 2013
NLRP3 inflammasome blockade inhibits VEGF-A-induced age-related macular degeneration.
Cell reports
Marneros AG
A-11132 was used in immunohistochemistry to study age-related macular degeneration and the roles played by VEGF-A and the NLRP3 inflammasome.
Thu Sep 12 00:00:00 EDT 2013
Mouse ghrelin-O-acyltransferase (GOAT) plays a critical role in bile acid reabsorption.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Kang K,Schmahl J,Lee JM,Garcia K,Patil K,Chen A,Keene M,Murphy A,Sleeman MW
A-11132 was used in Immunohistochemistry to study the physiological functions of the ghrelin O-acyltransferase/ghrelin system.
Sun Jan 01 00:00:00 EST 2012
mTrop1/Epcam knockout mice develop congenital tufting enteropathy through dysregulation of intestinal E-cadherin/β-catenin.
PloS one
Guerra E,Lattanzio R,La Sorda R,Dini F,Tiboni GM,Piantelli M,Alberti S
A-11132 was used in immunohistochemistry to determine the role of TROP1/EPCAM in congenital tufting enteropathy and develop an animal model
Tue Jun 11 00:00:00 EDT 2013
Paneth cell marker expression in intestinal villi and colon crypts characterizes dietary induced risk for mouse sporadic intestinal cancer.
Proceedings of the National Academy of Sciences of the United States of America
Wang D,Peregrina K,Dhima E,Lin EY,Mariadason JM,Augenlicht LH
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunohistochemistry
Tue Jun 21 00:00:00 EDT 2011
Vaccinia virus GLV-1h237 carrying a Walker A motif mutation of mouse Cdc6 protein enhances human breast tumor therapy in mouse xenografts.
International journal of oncology
Hofmann E,Grummt F,Szalay AA
A-11132 was used in Western Blotting to show that combining oncolytic virotherapy with agents that interfere with host cell DNA synthesis is a promising approach for cancer therapy.
Tue Mar 01 00:00:00 EST 2011
Enhanced tumor therapy using vaccinia virus strain GLV-1h68 in combination with a β-galactosidase-activatable prodrug seco-analog of duocarmycin SA.
Cancer gene therapy
Seubert CM,Stritzker J,Hess M,Donat U,Sturm JB,Chen N,von Hof JM,Krewer B,Tietze LF,Gentschev I,Szalay AA
A-11132 was used in western blot to investigate the use of oncolytic viruses for gene-directed enzyme prodrug therapy to treat breast cancer
Sat Jan 01 00:00:00 EST 2011
Wnt/β-catenin signaling is disrupted in the extra-toes (Gli3(Xt/Xt) ) mutant from early stages of forebrain development, concomitant with anterior neural plate patterning defects.
The Journal of comparative neurology
Fotaki V,Price DJ,Mason JO
A-11132 was used in immunohistochemistry to study the role of Gli3 during forebrain development in mice
Wed Jun 15 00:00:00 EDT 2011
Bacterial glucuronidase as general marker for oncolytic virotherapy or other biological therapies.
Journal of translational medicine
Hess M,Stritzker J,Härtl B,Sturm JB,Gentschev I,Szalay AA
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Western Blot
Tue Oct 11 00:00:00 EDT 2011
Interaction between axons and specific populations of surrounding cells is indispensable for collateral formation in the mammillary system.
PloS one
Szabó NE,Zhao T,Çankaya M,Stoykova A,Zhou X,Alvarez-Bolado G
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunohistochemistry
Mon Oct 17 00:00:00 EDT 2011
Understanding abnormal retinoid signaling as a causative mechanism in congenital diaphragmatic hernia.
American journal of respiratory cell and molecular biology
Clugston RD,Zhang W,Alvarez S,de Lera AR,Greer JJ
A-11132 was used in Immunohistochemistry to examine the role of retinoid signalling in the developing diaphragm and how its perturbation is a common mechanism in drug-induced congenital diaphragmatic hernia.
Mon Mar 01 00:00:00 EST 2010
Regulation of smoothened by Drosophila G-protein-coupled receptor kinases.
Developmental biology
Cheng S,Maier D,Neubueser D,Hipfner DR
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Immunofluorescence
Fri Jan 01 00:00:00 EST 2010
Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells.
Nucleic acids research
Nyabi O,Naessens M,Haigh K,Gembarska A,Goossens S,Maetens M,De Clercq S,Drogat B,Haenebalcke L,Bartunkova S,De Vos I,De Craene B,Karimi M,Berx G,Nagy A,Hilson P,Marine JC,Haigh JJ
Published figure using beta Galactosidase polyclonal antibody (Product # A-11132) in Western Blot
Wed Apr 01 00:00:00 EDT 2009
Tumor associated stromal cells play a critical role on the outcome of the oncolytic efficacy of conditionally replicative adenoviruses.
PloS one
Lopez MV,Viale DL,Cafferata EG,Bravo AI,Carbone C,Gould D,Chernajovsky Y,Podhajcer OL
A-11132 was used in immunohistochemistry - paraffin section to suggest that stromal cells contribute heavily to the outcome of the oncolytic efficacy of conditionally replicative adenoviruses
Fri Jun 12 00:00:00 EDT 2009
Chemokine receptor expression by neural progenitor cells in neurogenic regions of mouse brain.
The Journal of comparative neurology
Tran PB,Banisadr G,Ren D,Chenn A,Miller RJ
A-11132 was used in immunohistochemistry to study the involvement of chemokine receptor in neurogenesis
Tue Feb 20 00:00:00 EST 2007
LIM-kinase 2 and cofilin phosphorylation mediate actin cytoskeleton reorganization induced by transforming growth factor-beta.
The Journal of biological chemistry
Vardouli L,Moustakas A,Stournaras C
A-11132 was used in Western Blotting to define a novel pathway emanating from the TGF-beta type I receptor and leading to regulation of actin assembly, via the kinase LIMK2.
Fri Mar 25 00:00:00 EST 2005
Fission of pancreatic islets during postnatal growth of the mouse.
Journal of anatomy
Seymour PA,Bennett WR,Slack JM
A-11132 was used in Immunohistochemistry to demonstrate that islet fission is a mode of islet production in the postnatal pancreas of the mouse.
Sun Feb 01 00:00:00 EST 2004
Primitive adult hematopoietic stem cells can function as osteoblast precursors.
Proceedings of the National Academy of Sciences of the United States of America
Olmsted-Davis EA,Gugala Z,Camargo F,Gannon FH,Jackson K,Kienstra KA,Shine HD,Lindsey RW,Hirschi KK,Goodell MA,Brenner MK,Davis AR
A-11132 was used in immunocytochemistry to study the function as an osteoblast precursor by primitive adult hematopoietic stem cells
Tue Dec 23 00:00:00 EST 2003
The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation.
Cell
Tapon N,Ito N,Dickson BJ,Treisman JE,Hariharan IK
A-11132 was used in immunocytochemistry to study mutations in the Drosophila Tsc1 and Tsc2/gigas genes
Fri May 04 00:00:00 EDT 2001
Odorants stimulate the ERK/mitogen-activated protein kinase pathway and activate cAMP-response element-mediated transcription in olfactory sensory neurons.
The Journal of biological chemistry
Watt WC,Storm DR
A-11132 was used in immunohistochemistry - frozen section to propose that olfactory sensory neurons undergo long term adaptive changes mediated through cAMP-response element-mediated transcription
Fri Jan 19 00:00:00 EST 2001
The Rac GTPase-activating protein RotundRacGAP interferes with Drac1 and Dcdc42 signalling in Drosophila melanogaster.
The Journal of biological chemistry
Raymond K,Bergeret E,Dagher MC,Breton R,Griffin-Shea R,Fauvarque MO
A-11132 was used in immunohistochemistry to study interference with Dcdc42 and Drac1 signaling in Drosophila melanogaster by the Rac GTPase-activating protein RotundRacGAP
Fri Sep 21 00:00:00 EDT 2001
Apical, lateral, and basal polarization cues contribute to the development of the follicular epithelium during Drosophila oogenesis.
The Journal of cell biology
Tanentzapf G,Smith C,McGlade J,Tepass U
A-11132 was used in immunocytochemistry to identify mechanisms that regulate polarization of the follicular epithelium in Drosophila ovaries
Mon Nov 13 00:00:00 EST 2000
Engrailed and hedgehog make the range of Wingless asymmetric in Drosophila embryos.
Cell
Sanson B,Alexandre C,Fascetti N,Vincent JP
A-11132 was used in immunohistochemistry to observe the spread of Wingless within the embryonic epidermis of Drosophila
Fri Jul 23 00:00:00 EDT 1999
Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion.
Nature
Bellaiche Y,The I,Perrimon N
A-11132 was used in immunohistochemistry to show that tout-velu is required Hedgehog diffusion
Thu Jul 02 00:00:00 EDT 1998