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MA5-15859 targets c-Rel in indirect ELISA, IF and IHC applications and shows reactivity with Human and mouse samples.
MA5-15859 targets c-Rel in WB against recombinant c-Rel and transfected cell lysates only.
The MA5-15859 immunogen is purified recombinant fragment of human c-Rel expressed in E. Coli.
MA5-15859 detects c-Rel which has a predicted molecular weight of approximately 78 kDa.
The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA., RELB (604758), NFKB1, and NFKB2. These proteins are related through a highly conserved N-terminal region termed the 'Rel domain, ' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (Belguise and Sonenshein, 2007).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BCD541; C-Rel protein; C-Rel proto-oncogene protein; gemin 1; gemin-1; oncogene REL, avian reticuloendotheliosis; Proto-oncogene c-Rel; SMA; SMA1; SMA2; SMA3; SMA4; SMN; SMN2; SMNT; v-rel avian reticuloendotheliosis viral oncogene homolog
基因别名: C-Rel; REL
UniProt ID: (Human) Q04864
Entrez Gene ID: (Human) 5966, (Mouse) 19696
分子生物学功能:
Rel homology transcription factor