Invitrogen

hnRNP L Polyclonal Antibody

hnRNP L Antibody in Immunocytochemistry (ICC/IF)

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hnRNP L Antibody (PA5-88548) in ICC/IF

Immunofluorescence analysis of hnRNP L in 293T cells. Samples were incubated with hnRNP L Polyclonal antibody (Product # PA5-88548) using a dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

hnRNP L Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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产品信息

PA5-88548

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:50-1:200

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 282-589 of human HNRNPL (NP_0015242)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.05 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2804991

产品详细信息

Immunogen sequence: TWDYTNPNLS GQGDPGSNPN KRQRQPPLLG DHPAEYGGPH GGYHSHYHDE GYGPPPPHYE GRRMGPPVGG HRRGPSRYGP QYGHPPPPPP PPEYGPHADS PVLMVYGLDQ SKMNCDRVFN VFCLYGNVEK VKFMKSKPGA AMVEMADGYA VDRAITHLNN NFMFGQKLNV CVSKQPAIMP GQSYGLEDGS CSYKDFSESR NNRFSTPEQA AKNRIQHPSN VLHFFNAPLE VTEENFFEIC DELGVKRPSS VKVFSGKSER SSSGLLEWES KSDALETLGF LNHYQMKNPN GPYPYTLKLC FSTAQHAS; Positive Samples: U-87MG, HeLa, HepG2, A-549, HT-29, Mouse brain, Mouse ovary, Rat brain; Cellular Location: Cytoplasm, Nucleus, nucleoplasm

靶标信息

Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。