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mGluR5 Antibody (PA1-24637) in WB
Nutrients 2020 -
Figure 4 Effect of maternal and/or offspring exposure to a free-choice palatable (P) diet on the relative protein levels of: ( A ), GRIA1 ( B ), mGLUR5 ( C ), CB1 ( D ), CB2 ( E ), DAGLalpha ( F ), DAGLbeta ( G ), MAGL ( H ), NAPE-PLD ( I ) and FAAH ( J ) in the prefrontal cortex of male and female offspring in adulthood. Representative immunoblots ( K ). Data are expressed as the mean +- S.E.M. ( n = 4). S... View More
产品信息
PA1-24637
产品规格
已发表种属
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues Y D R R L A Q H K S E I E of mGluR5.
偶联物
Unconjugated
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2114053
产品详细信息
PA1-24637 is expected to cross react with human (100% conserved) and chicken (90% conserved) due to sequence homology.
靶标信息
GRK1 is a member of the guanine nucleotide protein-coupled (G protein) receptor kinase subfamily of Serine/Threonine kinase family. GRK1 phosphorylates rhodopsin and initiates its deactivation. G protein mediated phosphorylation promotes the binding of arrestin, which removes the receptor from the G-protein and terminates the receptor signal chain. GRK1 is farnesylated to promote membrane association. Studies have shown that GRK1 has been shown to be inhibited by recoverin, a Calcium binding protein. Diseases associated with GRK1 protein dysfunction include Oguchi Disease-2 and Hereditary Night Blindness.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
