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p39 Antibody (PA5-109505) in WB
Western blot analysis of p39 in mouse brain. Samples were incubated with p39 Polyclonal antibody (Product # PA5-109505) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-109505
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 170-310 of human CDK5R2 (NP_003927.1).
偶联物
Unconjugated
形式
Liquid
浓度
1.13 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2854916
产品详细信息
Immunogen sequence: PGGSPRRVIV QASTGELLRC LGDFVCRRCY RLKELSPGEL VGWFRGVDRS LLLQGWQDQA FITPANLVFV YLLCRESLRG DELASAAELQ AAFLTCLYLA YSYMGNEISY PLKPFLVEPD KERFWQRCLR LIQRLSPQML R
靶标信息
The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CDK5 activator 2; Cyclin-dependent kinase 5 activator 2; Cyclin-dependent kinase 5 regulatory subunit 2; p39; p39I
基因别名: B230310J22Rik; Cdk5r2; Nck5ai; p39
UniProt ID: (Mouse) O35926
Entrez Gene ID: (Mouse) 12570
neuron migration
cerebellum development
superior olivary nucleus maturation
hippocampus development
layer formation in cerebral cortex
positive regulation of protein kinase activity
positive regulation of calcium ion-dependent exocytosis
positive regulation of protein serine/threonine kinase activity
