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Product Details
PA5-17177
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide surrounding Thr90 of human p39
Conjugate
Unconjugated
Form
Liquid
Concentration
20 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10984443
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDK5 activator 2; Cyclin-dependent kinase 5 activator 2; cyclin-dependent kinase 5 activator isoform p39i; Cyclin-dependent kinase 5 regulatory subunit 2; cyclin-dependent kinase 5, regulatory subunit 2 (p39); neuronal CDK5 activator isoform; p39; p39I
Gene Aliases: B230310J22Rik; CDK5R2; NCK5AI; P39; p39nck5ai; RGD1562530
UniProt ID: (Human) Q13319, (Mouse) O35926
Entrez Gene ID: (Human) 8941, (Mouse) 12570, (Rat) 501164
regulation of cyclin-dependent protein serine/threonine kinase activity
neuron migration
cerebellum development
superior olivary nucleus maturation
hippocampus development
layer formation in cerebral cortex
positive regulation of calcium ion-dependent exocytosis
positive regulation of protein serine/threonine kinase activity
positive regulation of protein kinase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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