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p53DINP1 Antibody (PA5-29430) in IHC (P)
Immunohistochemical analysis of paraffin-embedded H1299 Xenograft, using p53DINP1 (Product # PA5-29430) antibody at 1:100 dilution. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-29430
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 1 and 59 of Human p53DINP1
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2546906
产品详细信息
Recommended positive controls: HeLa.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
A novel p53 inducible gene was identified and designated p53DINP1 (for p53-dependent damage-inducible nuclear protein). p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. p53DINP1/SIP is expressed in many tissues and induced by a variety of stress agents including UV stress, mutagenic stress, heat shock, and oxidative stress.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: p53-dependent damage-inducible nuclear protein 1; p53-inducible p53DINP1; p53DINP1; Stress-induced protein; Tumor protein p53-inducible nuclear protein 1
基因别名: P53DINP1; SIP; Teap; TP53DINP1; TP53INP1; TP53INP1A; TP53INP1B
UniProt ID: (Human) Q96A56
Entrez Gene ID: (Human) 94241
autophagosome assembly
transcription, DNA-templated
apoptotic process
response to stress
cell cycle arrest
negative regulation of cell proliferation
response to heat
positive regulation of autophagy
negative regulation of cell migration
cellular response to UV
regulation of apoptotic process
positive regulation of transcription, DNA-templated
autophagic cell death
cellular response to ethanol
cellular response to hydroperoxide
cellular response to methyl methanesulfonate
cellular oxidant detoxification
regulation of signal transduction by p53 class mediator
positive regulation of apoptotic signaling pathway
