Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PBNP-FITC
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide taken within aino acid region 100-150 on human proBNP protein.
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, store in dark
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
In cardiac tissue brain natriuretic peptide (BNP) is synthesized as 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 aa "signal" peptide and a 108 aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of 76 aa amino-terminal NT-proBNP and biologically active 32 aa BNP hormone molecule. Both proBNP and NTproBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications at patients with heart failure.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: BNP32; Brain natriuretic factor; Brain natriuretic factor prohormone; brain natriuretic peptide; brain type natriuretic peptide; Gamma-brain natriuretic peptide; Iso-ANP; natriuretic peptide precursor B; natriuretic peptide precursor type B; Natriuretic peptides B; natriuretic protein; NTproBNP; preproBNP; type-B natriuretic factor
基因别名: AA408272; BNF; BNP; NPPB
UniProt ID: (Human) P16860, (Rat) P13205, (Mouse) P40753
Entrez Gene ID: (Human) 4879, (Rat) 25105, (Mouse) 18158
response to hypoxia
negative regulation of systemic arterial blood pressure
cGMP biosynthetic process
inflammatory response
receptor guanylyl cyclase signaling pathway
heart development
regulation of blood pressure
response to organic cyclic compound
negative regulation of cell growth
response to lipopolysaccharide
positive regulation of urine volume
positive regulation of renal sodium excretion
response to drug
response to peptide hormone
negative regulation of smooth muscle cell proliferation
regulation of blood vessel size
response to calcium ion
cellular response to mechanical stimulus
positive regulation of collecting lymphatic vessel constriction
cell surface receptor signaling pathway
body fluid secretion
negative regulation of angiogenesis
regulation of vasodilation
regulation of vascular permeability
