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NeoBiotechnologies
CD52 (Epididymis-Specific Protein 5) Recombinant Rabbit Monoclonal Antibody (CD52, 2276R)
Application
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CD52 (Epididymis-Specific Protein 5) Antibody (1043-RBM1-P1ABX) in IHC (P)
Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human tonsil using CD52 (Epididymis-Specific Protein 5) Recombinant Monoclonal Antibody (Product # 1043-RBM1-P1ABX).
产品信息
1043-RBM1-P1ABX
产品规格
种属反应
Human,
Non-human primate
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
CD52, 2276R
抗原
Recombinant full-length human CD52 protein
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
靶标信息
CD52, also known as CAMPATH-1 antigen, is a glycoprotein that is expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes. It is involved in the regulation of immune responses and is being studied as a potential therapeutic target in various diseases, including multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders. CD52 is the target of alemtuzumab, a monoclonal antibody that is used to treat these conditions by depleting immune cells that express CD52.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cambridge pathology 1 antigen; CAMPATH-1 antigen; CD52; CD52 antigen; CD52 antigen (CAMPATH-1 antigen); CDw52; CDW52 antigen (CAMPATH-1 antigen); Epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; He5; HEL-S-171mP; Human epididymis-specific protein 5
基因别名: CD52; CDW52; HE5
UniProt ID: (Human) P31358
Entrez Gene ID: (Human) 1043
