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产品信息
H00130106-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CIB4 (NP_001025052.1, 1 a.a. approximately 185 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGQCLRYQMH WEDLEEYQAL TFLTRNEILC IHDTFLKLCP PGKYYKEATL TMDQVSSLPA LRVNPFRDRI CRVFSHKGMF SFEDVLGMAS VFSEQACPSL KIEYAFRIYD FNENGFIDEE DLQRIILRLL NSDDMSEDLL MDLTNHVLSE SDLDNDNMLS FSEFEHAMAK SPDFMNSFRI HFWGC
靶标信息
CIB4 (calcium and integrin-binding family member 4) is a 185 amino acid protein that contains three EF-hand domains. CIB4 is closely related to CIB (CIB has one less EF-hand domain), which is known to bind to Integrin alpha II beta in platelets and is involved in signal transduction. The gene encoding CIB4 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorders itosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstrom syndrome, is caused by mutationsin the ALMS1 gene, which maps to chromosome 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Calcium and integrin-binding family member 4
基因别名: CIB4; KIP4
UniProt ID: (Human) A0PJX0
Entrez Gene ID: (Human) 130106
