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Application
FIGURE: 1 / 1
FXYD1 Antibody (PA5-109744) in WB
Western blot analysis of FXYD1 in extracts of various cell lines. Samples were incubated with FXYD1 Polyclonal antibody (Product # PA5-109744) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-109744
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-92 of human FXYD1 (NP_005022.2).
Conjugate
Unconjugated
Form
Liquid
Concentration
1.46 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2855155
Product Specific Information
Immunogen sequence: MASLGHILVF CVGLLTMAKA ESPKEHDPFT YDYQSLQIGG LVIAGILFIL GILIVLSRRC RCKFNQQQRT GEPDEEEGTF RSSIRRLSTR RR
Target Information
This gene encodes a member of the FXYD family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity and act as an accessory protein of Na,K-ATPase. Alternatively spliced transcript variants have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FXYD domain-containing ion transport regulator 1; Phospholemman; Sodium Potassium ATPase; Sodium/potassium-transporting ATPase subunit FXYD1
Gene Aliases: 0610012C17Rik; 1110006M24Rik; Fxyd1; Plm; Pml
UniProt ID: (Mouse) Q9Z239, (Rat) O08589
Entrez Gene ID: (Mouse) 56188, (Rat) 58971
transport
ion transport
chloride transport
positive regulation of organic acid transport
regulation of cytosolic calcium ion concentration
regulation of cardiac muscle cell contraction
regulation of cardiac muscle cell membrane potential
positive regulation of sodium ion export from cell
positive regulation of inorganic anion transmembrane transport
regulation of sodium ion transmembrane transporter activity
brain development
chloride transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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