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A suggested positive control is EL4 cell lysate.
PA5-20751 can be used with blocking peptide PEP-0865.
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1, 000 members and is the largest known class of molecular targets with proven therapeutic value. GPR3 is an orphan receptor with constitutive G signaling activity. GPR3 modulates a number of brain functions, including behavioral responses to stress, neurite outgrowth and amyloid-beta peptide generation suggesting that it may play a role in Alzheimer's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ACCA orphan receptor; adenylate cyclase constitutive activator; G protein-coupled receptor R4; G-protein coupled receptor 3; G-protein-coupled receptor R4; GPCR21; Hacca; OTTHUMP00000043209
Gene Aliases: ACCA; Gpcr20; Gpcr21; Gpcr3; GPR3
UniProt ID: (Human) P46089, (Mouse) P35413, (Rat) Q8K1Q3
Entrez Gene ID: (Human) 2827, (Mouse) 14748, (Rat) 266769
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